Sex Development

Question 1

Girls with Turner syndrome (45, X) have ______ intellectual disability.

Answer 1

no

Question 2

Turner syndrome occurs in approximately _____ girls.

Answer 2

1/2,500

Question 3

______ is required for Turner syndrome girls to go through puberty.

Answer 3

Hormone therapy

Question 4

Boys with Klinefelter syndrome often have _____, a condition characterized by the urethra opening on the underside of the penis.

Answer 4

hypospadias

Question 5

Though not more common among felons, as previously thought, those with _____ typically have emotional problems and learning disabilities.

Answer 5

Jacobs syndrome (XYY)

Question 6

Triple X syndrome is characterized by ______.

Answer 6

tall stature, seizures, kidney problems, and learning disabilities

Question 7

_____ protein, which is inhibited by SOX9, is responsible for differentiation of the ovaries.

Answer 7

WNT4

Question 8

The androgen receptor gene is found on the ___ chromosome.

Answer 8

X

Question 9

Androgen Insensitivity Syndrome (AIS) was previously called ________.

Answer 9

testicular feminization

Question 10

5-alpha reductase deficiency results from _____.

Answer 10

insufficient ability of the body to convert testosterone to dihydrotestosterone

Question 11

Children with ______ appear female until puberty and then masculinize at puberty with increased testosterone production.

Answer 11

5-alpha reductase deficiency

Question 12

_____ is a transcription factor for SRY; mutations in it can lead to sex reversal and renal problems.

Answer 12

WT1