sexual disorders Flashcards
(41 cards)
sexual desire disorders
female sexual interest disorder
male hypoactive sexual desire disorder
sexual aversion disorder
hypoactive sexual interest d/o
1- persistently deficient sexual fantasies/ desires for sexual activity for one’s age and context
2- causes distress or difficulty
3- not better accounted for by another disorder, not d/t substance or general medical condition
tx for female sexual interest disorder
couples therapy
bremelanotide (inc libido in 90% pts), subQ method in testing now (intranasal had adverse effects on BP)
flibanserin- a 5HT-1a agonist, 5HT-2a antagonist; *Severe hypotension with EtOH and CYP3A4 inhibitors
male hypoactive sexual desire disorder
persistently or recurrently deficient sexual/erotic thoughts or fantasies and desire
min 6 months
causes distress
not explained by another disorder
tx male hypoactive sexual desire disorder
psychotherapy, testosterone
? bremelanotide
D2-agonist (cabergoline, pramipexole, ropinirole) - may inc desire but may lead ot hypersexuality condition/ psychosis
sexual aversion disorder (DSM4)
1- persistent/recurrent extreme aversion and avoidance of genital contact w sexual partner
2- causes distress or difficulty
3- not explained by another axis 1 disorder (except another sexual dysfunction)
tx sexual aversion disorder
graduated exposure
CBT
stress reduction, relaxation
relation therapy (if relation or communication problems)
sexual aversion from PTSD and tx
sexual abuse or other traumatic experiences caused disorder
tx: work through these disorders
sexual arousal disorders
female/male sexual arousal disorder
male erectile disorder
female sexual arousal disorder
1- persistent/recurrent inability to attain or maintain until completion of activity, an adequate lubrication-swelling response of excitement
2- causes distress or difficulty
3- not better accounted for by axis 1 d/o (except sexual dysfunction), and not d/t substance or general medical condition
sexual arousal disorder tx
focus on relationship issues, improved communication (verbal and nonverbal), non-sexual intimacy, education about sexuality
topical cream Femprox for females (under development)- contains PGE1
male erectile disorder
1- persistent/recurrent inability to attain or maintain adequate erection until completion of activity
2- causes distress or difficulty
3- not better accounted for by axis 1 d/o (except sexual dysfunction), substance, or medical condition
erectile dysfunction tx
PDE5-I (sildenafil, vardenafil, tadalafil)
injection therapy: papaverine, phentolamine, PGE1
penile prosthesis or pump
orgasmic disorders
female and male orgasmic disorders
premature ejaculation
delayed ejaculation
orgasmic disorder criteria
1- persistent/recurrent delay or absence of orgasm following normal sexual excitement phase (although there is always variation in type/intensity of stimulation that triggers orgasm)
2- causes distress or difficulty
3- not accounted for by another d/o, substance, medical condition
tx orgasmic disorders
Hitachi magic wand
sialidase (enzyme to regrow damaged nerve)
yohimbine - male impotence
Wellbutrin ?
cabergoline (D2-agonist) - dec prolactin - may help achieve orgasm partially or fully
premature ejaculation
1- persistent/recurrent ejaculation with minimal stimulation before, on, soon after penetration and before desired; must account for age, recent frequency of sexual activity, duration of excitement phase, etc.
2- distress
3- not d/t substance (like opioid withdrawal)
tx premature ejaculation
SSRI
tramadol- atypical oral analgesic; mu agonist and inc NE and 5HT
clomipramine (TCA)- side effect = delayed ejaculatory response
desensitizing creams- apply to penis, may cause contamination and dec sensitivity of partner
delayed ejaculation
delayed ejaculation during 75%+ partnered sexual activity
minimum of 6 months duration
tx: sex therapy, no known meds yet
sexual pain disorders
dyspareunia, vaginismus
dyspareunia
1- recurrent/persistent genital pain a/w sexual intercourse in male or female
2- distress
3- not d/t vaginismus/lack of lubrication exclusively, not d/t axis 1 d/o, substance, or medical condition
causes of dyspareunia
congenital: endometriosis, vaginal septa, thickened undilatable hymen, introitus hypoplasia, ovarian cysts
acquired: infection, vulvar vestibulitis, tumor (e.g. fibroid), xerosis (dryness, esp post-menopause), interstitial cystitis, uterine prolapse, surgical complications
acq or cong: retroverted uterus, vaginismus
gender differences in dyspareunia
significantly more common in women (20%)
causes in men: infection, interstitial cystitis, Peyronie’s disease, tight foreskin, frenulum brevis
tx dyspareunia
sexual lubricant, positions that limit depth of penetration, estrogen tx (vaginal dryness in post-menopausal women), surgery (some cases)