Sexually Transmitted Diseases

Question 1

Primary or secondary infection in preg mom is worse?

Answer 1

primary cause no IgG

Question 2

how to test for infections like viruses?

Answer 2

serology

Question 3

If a serology report against ‘x’ is negative what could it mean?

Answer 3

1. not exposed
2. haven’t mounted response
3. viral incubation period

Question 4

IgM +ve means?

Answer 4

• depends if you can compare to a previous result

- lasting is variable

Question 5

CMW IgM lasts?

Answer 5

3-18 months to 4 years…

Question 6

+ve IgG means?

Answer 6

past infection or vaccination

Question 7

what happens if you can’t get rising titres?

Answer 7

Avidity of Antibodies

Question 8

Epstein Barr virus could do what to serology?

Answer 8

polyclonal B-cell response with glandular fever, range of antibodies produced

Question 9

if positive result for virus in preg, could mean 2 things:

Answer 9

1. protective for future preg (eg/ rubella)

2. not protective, chronic (HIV)

Question 10

What kind of bug is toxoplasma gondii?

Answer 10

protozoa

Question 11

Signs of Parvo B19?

Answer 11

slapped cheek

maculopapular rash

Question 12

Parvo does what to body?

Answer 12

decreases reticolocyte lifespan: anaemia

Question 13

Rubella management in preg?

Answer 13

Termination if high risk fetal morbidity

Question 14

CMV treatment?

Answer 14

Gancyclovir or termination

Question 15

Varicella in first trimester as primary infection results?

Answer 15

limb hypoplasia, microcephaly, cataracts, mental

Question 16

CMV in preg, results in affected fetus?

Answer 16

hearing, visual, psychomotor defects

Question 17

treatment for toxoplasmosis in preg woman?

Answer 17

macrolide

Question 18

Rubella greatest damage when?

Answer 18

first trimester

Question 19

Parvo in fetus? how treat?

Answer 19

Hydrops Foetalis

Intrauterine transfusion

Question 20

HSV on fetus?

Answer 20

HSV sepsis syndrome

often fatal

Question 21

HSV treatment and management?

Answer 21

Acyclovir for mom for suppression

C-section to avoid perinatal

Question 22

Why test for syphilis in woman who had sex with man with gonorrhoea?

Answer 22

chances are that man who had gonorrhoea had sex with another man, may have syphilis or HIV so test for syphilis/HIV in absence of other info

Question 23

Gonorrhoea look how under microscopy?

Answer 23

gram -ve diplococci inside neutrophils

Question 24

see big purple oval under microscopy from cervical swab?

Answer 24

Candida Albicans

Question 25

Gonorhoea management?

Answer 25

3rd gen cefixime

Question 26

Chlamydia treatment?

Answer 26

Azithromycin (macrolide)

Question 27

syphilis treatment?

Answer 27

penicillin

Question 28

Candida Albicans treatment?

Answer 28

antifungal: amphotericin

Question 29

Presence of hepatitis Be (HBe) antigen and absence of HBe antibody usually indicates?

Answer 29

active hepatitis B virus (HBV) replication and high infectivity

Question 30

-ve Hep B Core antibody means?

Answer 30

no infection within last 6/12

Question 31

+ve Hep B Core antibody means?

Answer 31

recent acute hepatitis B infection

Question 32

Absence of HBe antigen with appearance of HBe antibody is?

Answer 32

loss of HBV infectivity

Question 33

Monospot test for glandular fever: which virus?

Answer 33

EBV -polyclonal B cells, sheep RBCs

Question 34

CMV worse when?

Answer 34

primary infection in mom