SFII Immunology

Question 1

What cell can activate a naive T cell?

Answer 1

Dendritic cell (DC)

Question 2

Interleukins aka?

Answer 2

Cytokines

Question 3

What cells are found in the lymph node cortex?

Answer 3

B cells

Question 4

What cells are found in the lymph node paracortex?

Answer 4

T cells

Question 5

What cells are found in the lymph node inner medulla?

Answer 5

Plasma and macrophages

Question 6

B cell progenitor lineage

Answer 6

Lymphoid

Question 7

T cell progenitor lineage

Answer 7

Lymphoid

Question 8

Dendritic cell progenitor lineage

Answer 8

Both

Question 9

Granulocyte progenitor lineage

Answer 9

Myeloid

Question 10

Platelet progenitor lineage

Answer 10

Myeloid

Question 11

Erythrocyte progenitor lineage

Answer 11

Myeloid

Question 12

Monocyte progenitor lineage

Answer 12

Myeloid

Question 13

What is the function of CCR7?

Answer 13

Chemokine that sends DC to lymph nodes to activate naive T cells

Question 14

MHC I responds to

Answer 14

Cytosolic pathogen - virus / malignant cells

Question 15

MHC II responds to

Answer 15

Extracellular pathogen - bacteria

Question 16

MHC I activates which T cells?

Answer 16

CD8

Question 17

MHC II activates which T cells?

Answer 17

CD4

Question 18

Stem cell CDs

Answer 18

31, 34

Question 19

Leukocyte CDs

Answer 19

45

Question 20

Granulocyte CDs

Answer 20

15, 24, 45, 114, 182

Question 21

Monocyte CDs

Answer 21

11a, 14, 45, 91, 114

Question 22

T lymphocyte CDs

Answer 22

3, 45

Question 23

T helper CDs

Answer 23

3, 4, 45

Question 24

T regulatory CDs

Answer 24

FOXp3, 4, 25

Question 25

Cytotoxic T CDs

Answer 25

3, 8, 45

Question 26

B lymphocyte CDs

Answer 26

19, 20, 24, 45

Question 27

Thrombocyte CDs

Answer 27

45, 61

Question 28

NK CDs

Answer 28

3, 16, 30, 31, 56

Question 29

Do T or B cells respond to epitome alone?

Answer 29

B

Question 30

Do T or B cells respond to epitome with MHC?

Answer 30

T

Question 31

TH1 function

Answer 31

Macrophage-mediated destruction of intracellular pathogens

Question 32

TH2 function

Answer 32

IgE for parasite destruction

Question 33

TH17 function

Answer 33

Neutrophil recruitment (bacterial infection)

Question 34

TFH function

Answer 34

Stimulate antibodies from B cells

Question 35

Treg cell function

Answer 35

Suppress T cell response