Shock an Fluid Rescucitation Flashcards

1
Q

What are the clinical alterations seen in shock?

A
  • hypotension
  • tachycardia
  • tachypnea
  • altered mental status
  • oliguria/anuria
  • skin changes
  • metabolic derangements (Anion gap metabolic acidosis, BUN/Cr, Coagulation factors, lactic acidosis, changes in SVO2/ScVO2)
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2
Q

what are the 4 major types of shock?

A

Hypovolemic

Distributive

Cardiogenic

Obstructive

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3
Q

Hypovolemic Shock:

  • causes
  • PE findings
  • describe how each of the following are affected:
  • -CVP
  • -PCWP
  • -SVO2
  • -SVR
  • -CO
  • -Pulse pressure
  • -DBP
  • -extremities
  • -cap refill
A

Causes:
-hemorrhage, GI/GU losses, dehydration

PE findings:

  • diarrhea, polyuria, poor intake
  • flat, non-distended neck veins

CVP: LOW (preload; filling pressure in the right side of the hear)

PCWP: LOW (wedge pressure)

SVO2: LOW (how much O2 is still attached to hgb right before entering RA)

SVR: HIGH (body tries to compensate by vasoconstriction)

CO: LOW

Pulse pressure: LOW

DBP: LOW

Extremities: cold/clammy

cap refill: greater than 2 seconds

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4
Q

T/F: significant drops in blood pressure are generally not manifested until class III hemorrhage develops and up to 30% of pts blood volume has been lost.

Describe the classes of hemorrhage according to ATLS.

A

True.

Class 1: blood volume up to 15%. HR is minimally elevated or normal, no change in BP, pulse pressure, or RR.

Class II: 15-30% blood volume loss and manifested clinically as tachycardia (HR100-120), tachypnea (RR20-24), and decreased pulse pressure. SBP doesnt change much. Skin is cool and clammy, cap refill may be delayed.

Class III: 30-40% blood volume loss; significant drop in BP andd changes in mental status. HR greater than 120BPM, RR is markedly elevated, urine output is diminished, cap refill is delayed.

Class IV: greater than 40% blood loss leading to significant depression in blood pressure and mental status. SBP less than 90, most are in hypotensive shock. Pulse pressure is narrow, tachycardia is marked, urine output is minimal or absent. Skin is cold, pale, and cap refill is delayed.

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5
Q

What are the signs of hypovolemia?

  • mild-moderate hypovolemia
  • blood volume loss at least 15%
  • blood volume loss of at least 40%
A

mild/moderate: resting tachycardia

Blood volume loss of 15%: orthostatic hypotension (decrease in SBP of more than 20mmhg and/or increase in hear rate of 20BPM when moving from lying to standing)

Blood volume loss of at least 40%: supine hypotension.

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6
Q

What is the triad of death?

A

Coagulopathy, metabolic acidosis, hypothermia. (this is a viscious cycle; one thing leads to the next..)

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7
Q

Who requires Massive Transfusion products required?

What is the protocol for this?

Indications? (how many units of blood are required)

A

Transfusion for severe ongoing hemorrhage; for trauma patients with ongoing hemorrhage that is unlikely to be controlled quickly or adequately.

Protocol:
-Immediate transfusion of blood products, 1:1:1 ratio of PRBC, FFP, and platelets.

Indications:
-when pt requires more than 4 units of PRBC over one hour or 10 or more units in over 12-24hrs.

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8
Q

Cardiogenic Shock:

  • causes
  • PE findings
  • describe how each of the following are affected:
  • -CVP
  • -PCWP
  • -SVO2
  • -SVR
  • -CO
  • -Pulse pressure
  • -DBP
  • -extremities
  • -cap refill
A

Causes: “pumps broken”

  • ischemia
  • cardiomyopathy
  • mechanical
  • arrhythmia

PE:

  • chest pain
  • orthopnea
  • PND
  • JVD
  • Peripheral/pulmonary edema
  • S3 gallop

CVP: HIGH

PCWP: HIGH

SVO2: LOW

SVR: HIGH

CO: LOW

PULSE PRESSURE: NARRROW/LOW

DBP: LOW

EXTREMITIES: COLD

CAP REFILL: GREATER THAN 2 SECONDS

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9
Q

Tx cardiogenic shock

A

Tx: improve CO while reducing myocardial workload.

  • be careful with IV fluids
  • consider inotropic and.or vasopressor support
  • manage underlying cause (revascularization, rhythm conversion, etc)
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10
Q

Distributive Shock

  • cause
  • PE findings
  • describe how each of the following are affected:
  • -CVP
  • -PCWP
  • -SVO2
  • -SVR
  • -CO
  • -Pulse pressure
  • -DBP
  • -extremities
  • -cap refill
A

Cause:
“Pipes are the wrong size”
-loss of fluid into the extravascular thrid space
-sepsis, neurogenic injury, anaphylaxis, adrenal crisis

PE:

  • Hx of known allergy
  • spinal injury
  • fever/infectious sx
  • warm edematous extremities

CVP: LOW (+/-)

PCWP: LOW (+/-)

SVO2: HIGH (train is sent out of the station but its going too fast for the passengers to get off at any of the stops)

SVR: LOW

CO: HIGH (+/-)

PULSE PRESSURE: WIDE/NARROW

DBP: LOW

EXTREMITIES: WARM

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11
Q

Tx of anaphylactic shock

Tx of adrenal crisis

Tx neurogenic shock

A

-anaphylactic shock
IV fluid boluses

IV antihistamines

IV corticosteroids

IM epi

-Adrenal Crisis:
support hemodynamics with IV fluids and pressors as necessary
-stress dose steroids (hydrocortisone, 50mg q8hr)

-Neurogenic shock
IV fluids

pressor support

Atropine, dopamine, transcutaneous pacing as necessary for bradycardia

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12
Q

Obstructive Shock:

  • causes
  • PE findings
  • describe how each of the following are affected:
  • -CVP
  • -PCWP
  • -SVO2
  • -SVR
  • -CO
A

“Youve got yourself a stopped pipe”

Cause:

  • impaired cardiac filling
  • cardiac tamponade, pericarditis, tension pneumo, PE

PE findings:

  • Becks Triad (low arterial pressure, distended neck veins, distant muffled heart sounds)
  • asymmetric breath sounds
  • friction rub
  • pulsus paradoxus
CVP: +/- 
PCWP: +/- 
SVO2: +/- 
SVR: HIGH 
CO: LOW
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13
Q

Obstructive SHock:

  • treatment for each of the following:
  • -cardiac tamponade
  • -pulmonary embolism
  • -tension pneumothorax
A

Cardiac tamponade: IV fluids, emergent pericardiocentesis

Pulmonary embolism: IV fluids, vasopressor support, thrombolytics?

Tension pneumo: IV fluid, emergent needle thoracostomy followed by chest tube

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14
Q

When it all hits the fan keep your algorithm simple… what are the 4 categories you should start with for your DDX?

A

Hypovolemic

Distributive

Cardiogenic

Obstructive

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15
Q

What are the general principles of resuscitation?

What hgb level requires blood transfusion?

A

-A, B, C’s

Hemodynamic/ventilatory support:

  • improve the components of oxygen delivery/consumption
  • decrease tissue metabolic demands (consider mechanical ventilation)

Assessment and optimization of fluid status

Management of underlying condition.

-Previously a target Hgb of 10 was recommended until the TRICC Trial, now transfusion goal is hgb of 7, unless cardiac ischemia.

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16
Q

Inotropes and vasopressors are indicated with hypotension/hypoperfusion refractory to adequate volume resuscitation…
-discuss the catecholamine receptors and where they act.

Which receptor does NE mainly work on? what are the consequences of this?

NE is used first line for which type of shock?

A

Catecholamines:

  • Beta 1: increases cardiac contractility
  • beta 2: induces smooth muscle vasodilation
  • alpha 1: arterial vascular smooth muscle contraction
  • D1/D2: vasodilation of renal/splanchnic vasculature

NE works on alpha 1 receptors.
-consequences: vasoconstriction without impacting CO or HR.

NE is first line in septic shock, also recommended in undifferentiated shock states.

17
Q

Vasopressin:
-acts on which receptors? consequences ?

Epinephrine:
-acts on which receptors?
Consequences?

A

Vasopressin: (ADH)
-acts on V1 (vasculature) and V2 (renal) receptors

consequenes: V1 stimulates smooth muscle contraction

V2 increases water resorption at collecting ducts.

Epinephrine:
-B1(contractility) & 2(vasodilation), alpha 1 (vasoconstriction)

-consequences: apoptosis and contraction band necrosis (can cause cardiac toxicity)

18
Q

Dopamine:
-acts on which receptors? consequences?

Dobutamine:
-acts on which receptors? consequences?

A

Dopamine:

  • *natural precursor to NE
  • acts on B1 and alpha 1
  • -beta 1 promotes NE release
  • -alpha 1 = vasoconstriction

Dobutamine:

  • Beta 1 and 2
  • alpha 1

-consequence: increases myocardial oxygen demand, subject to tachyphylaxis (acute rapidly diminishing response to successive doses of a drug rendering it less effective)

19
Q

Give me the “run down” of a code blue.

During a code is it okay to get central line placement?

A

in first 30 seconds:

  • backboard for high quality CPR
  • pads on
  • timer

in first 90seconds:
-assign jobs

The rest:

  • hx
  • H/Ts
  • Meds
  • repeat
  • pulse and rhythm check: goal less than 10 seconds

No, dont do it. Peripheral is preferred, if you cannot get peripheral IV go straight to IO!