Shock + RUSH Protocol Flashcards
State of inadequate tissue perfusion leading to hypoxia and cell death
Shock
Inflammatory response to microorganisms, or invasion of sterile host tissue
Infection
Viable bacteria in the blood
Bacteremia
T > 38 or < 36
HR > 90
RR > 20
WBC > 12,000 or < 4,000 or > 10% bands
PaCO2 < 35
SIRS
(must meet at least 2 of the criteria)
SIRS
+
Source of Infection
Sepsis
Hypotension
+
Severe Sepsis
aka hypoperfusion causing hypoxia and cell death
Septic Shock
Severe Sepsis = sepsis + lactic acidosis, SBP < 90 or a drop > 40
Who gets septic shock?
Anyone can
Increased risk for immunocompromised (DM, Medicated, Asplenic, etc.)
Increased risk for those at “extremes of age”
Tx for septic shock
Abx (early goal directed therapy)
+
Fluid (most often crystalloid)
4 Classic Types of Shock
- Hypovolemic (secondary to hemorrhage or loss of other bodily fluid)
- Cardiogenic
- Distributive (sepsis, anaphylaxis, neurogenic shock)
- Obstructive (pericardial tamponade, tension pneumo, PE)
Classes of Hemorrhagic Shock
Class I-IV
You can lose up to 30% of your blood volume (Class II) before your BP begins to decrease (Class III)
Class IV: >2000 ml blood loss (40% or more),
HR > 140, RR > 35
Tx for Hemorrhagic Shock
Find the bleeding
Stop the bleeding
*Reverse coagulopathies (ASA, Warfarin)
Replace blood and support patients
*Mainly applies to older patients
Which areas of the body are you most likely to bleed to death from?
Abdomen
Femur/Thigh
Pelvis
Chest
Externally
When do you start hypotensive resuscitation for someone in hemorrhagic shock?
If their BP drops below 80
Difference between hypotensive resuscitation and tx for hypovolemic shock
Hypotensive resuscitation = give blood
Hypovolemic shock = give crystalloid
Risk factors for anaphylaxis
Poorly controlled asthma
Previous anaphylaxis
Previous exposure to sensitizing agent
Most common causes of anaphylaxis
Antibiotics (esp. B-lactam): 400-800 deaths
Insects: < 100 deaths
Food: 11 deaths
Severe systemic hypersensitivity that may include hypotension or airway compromise
Anaphylaxis
IgE-dependent mast cell, basophil release
Anaphylactoid
Non-IgE mediated
Same final common pathway as anaphylaxis
No sensitizing exposure required
Primary Tx for anaphylaxis
Epi (no absolute contraindications)
0.1 mg IV or 0.3-0.5 mg IM (i.e., give less potent when IV)
Stabilizing Treatment for Anaphylaxis
Intubate sooner rather than later
Fluid resuscitation for hypotension
Steroids
Antihistamines (H1 & H2)
Tx bronchospasm
Glucagon (if on β-blockers)
Neurogenic Shock
Disruption of sympathetic outflow:
Blunt trauma (usually C-spine)
Sympathetic roots T1-L2
Unopposed vagal tone
Hypotension + Bradycardia
Neurogenic Shock vs Spinal Shock
Spinal shock = total loss of spinal reflex activity AT AND BELOW injury level
Tx of Neurogenic Shock
Assume hemorrhage (even w/ bradycardia)
Stop secondary injury
Fluids
Pressors
Cardiogenic Shock
Decreased cardiac output despite adequate volume (tissue hypoperfusion)
Usually results from AMI