SIADH Flashcards
(5 cards)
1
Q
what is SIADH
A
hyponatraemia secondary to the dilutional effects of excessive water retention
2
Q
what is ADH
A
also known as vasopressin
leads to water retention, dilutional hyponatraemia
3
Q
causes of SIADH
A
malignancy: small cell lung cancer, pancreas and prostate
neuro: stroke, subarachnoid, subdural, meningitis
infections: tuberculosis, pneumonia
drugs: sulfonylureas, SSRIs, tricyclics, carbamazepine, vincristine, cyclophosphamide
4
Q
investigations for SIADH
A
urine osmolality: high
serum osmolality: low
urine sodium concentration: high
5
Q
management of SIADH
A
correct slowly
fluid restriction
demeclocycline
ADH receptor antagonists
