SIADH

Question 0

What can cause SIADH?

Answer 0

Malignancy (especially bronchial small cell carcinoma)
Infection (particularly pneumonia, but any infection can cause)
Cerebral disease (SAH, meningitis)
Medications (SSRIs, carbamazepine, thiazides)

Question 1

What features are needed to diagnose SIADH?

Answer 1

Euvolaemic patient
Hyponatraemia
Low serum osmolarity
High urine sodium 
High urine osmolarity

Exclusion of other causes:

• Glucocorticoid deficiency
• Hypothyroidism
• Diuretic therapy

Question 2

What is the initial treatment of SIADH?

Answer 2

Fluid restriction