Side Effects

Question 1

AE: flushing

Answer 1

Vancomycin, niacin, calcium channel blockers (dihyrdroperidine), adenosine

Question 2

AE: coronary vasospasm

Answer 2

Cocaine, amphetamines, ergots, triptans

Question 3

AE: dilated cardiomyopathy

Answer 3

Danorubicin, doxorubicin

Question 4

AE: torsades de points

Answer 4

Sodium and potassium channel blockers, macrolides, haloperidol, protease inhibitors, choloquine

Question 5

AE: thrombocytopenia

Answer 5

Heparin, cimetidine

Question 6

AE: Agranulocytosis

Answer 6

Colchine, carbamazapine, clozapine, PTU, methimazole, dapsone

Question 7

AE: aplastic anemia

Answer 7

Chlorampenicol, benzene, NSAIDs, PTU, methimazole

Question 8

AE: Gray baby syndrome

Answer 8

Chlorampenicol

Question 9

AE: hemolysis in G6PD def

Answer 9

“Spleen purges nasty inclusions from damaged cells”

Isoniazid, sulfonamides, primaquine, aspirin (high dose), ibuprofen, nitrofurantoin, dapsone, fava beans, naphthalene

Question 10

AE: thrombosis

Answer 10

OC

Question 11

AE: Pulm fibrosis

Answer 11

Amiodarone, busulfan, bleomycin

Question 12

AE: cough

Answer 12

ACE inhibitors

Question 13

AE: pseudomembranous colitis

Answer 13

Clindamycin, amoxicillin/ampicillin

Question 14

AE: hepatic necrosis

Answer 14

Acetaminophen, halothane, mushrooms (Amanita phalloides), valproic acid

Question 15

AE: hepatitis

Answer 15

isoniazid

Question 16

AE: tertiary adrenal insufficiency

Answer 16

Corticosteroid withdrawal

Question 17

AE: Gynecomastia

Answer 17

Spironolactone, THC, Alcohol, Cimetidine, Ketoconazole, Estrogens, Digoxin
“STACKED”

Question 18

AE: hot flashes

Answer 18

Tamoxifen, Clomiphene

Question 19

AE: hypothyroidism

Answer 19

Amiodarone, lithium, sulfonamides

Question 20

AE: Gout

Answer 20

Diuretics (loop and thiazide), niacin, cyclosporine, pyrazinamide

Question 21

AE: gingival hyperplasia

Answer 21

Phenytoin, verapamil

Question 22

AE: osteoporosis

Answer 22

Corticosteroids, heparin

Question 23

AE: Steven Johnson syndrome

Answer 23

Carbamazapine, lamotrigine, allopurinol, phenytoin, phenobarbital, penicillin, ethosuximide, RASH, sulfonamides
“CLAPPPERS”

Question 24

AE: Drug induced Lupus

Answer 24

Sulfonamides, Hydralazine, Isoniazid, Procainamide, Phenytoin
“SHIPP”

Question 25

AE: tendonitis

Answer 25

Fluoroquinolones

Question 26

AE: interstitial nephritis

Answer 26

NSAIDs, furosemide, anitbiotics

Question 27

AE: DI

Answer 27

Lithium, demeclocyline

Question 28

AE: fanconi syndrome

Answer 28

expired tetracycline

Question 29

AE: hemorrhagic cystitis

Answer 29

Cyclophosphamide, ifosfamide

Question 30

AE: Parkinson like syndrome

Answer 30

Metoclopramide, antipsychotics, reserpine

Question 31

AE: Cinchonism

Answer 31

Quinidine, quinine

Question 32

AE: seizures

Answer 32

Bupropion, imipenem/cilastin, isoniazid, tramadol, metoclopramide, benzo/alcohol withdrawal

Question 33

AE: tardive dyskinesia

Answer 33

Antipsychotics, metoclopramide

Question 34

AE: disulfiram like reaction

Answer 34

Metronidazole, certain cephalosporins, probarbazine, first gen sulfonylureas, disulfiram

Question 35

AE: nephro + neuro

Answer 35

Aminoglycosides, cisplatin, polymixins

Question 36

AE: nephro + ototoxicity

Answer 36

Aminoglycosides, vanc, loop diuretics, cisplatin

Question 37

AE: anticholinergic effects

Answer 37

atropine, TCAs, H1 blockers, low potency neuroleptics

Question 38

AE: hyperglycemia

Answer 38

corticosteroids and protease inhibitors

Question 39

AE: megaloblastic anemia

Answer 39

Phenytoin, methotrexate, sulfa drugs

Question 40

AE: photosensitivity

Answer 40

Sulfonamides, Amiodarone, Tetracyclines | "SAT for a photo"

Question 41

Drugs with low therapeutic index

Answer 41

digoxin, lithium, warfarin, theophylline