Side Effects Flashcards
1
Q
antipsychotics
A
first generation - extrapyramidal
increased prolactin weight gain hyperglycaemia sexual dysfunction tachycardia arrhythmia hypotension neuroleptic malignant syndrome/oculogyric crisis/acute dystonic reactions blood dyscrasia
2
Q
bisphosphonates
A
reflux
atypical fractures
osteonecrosis jaw
osteonecrosis external auditory canal
3
Q
sulphonylureas
A
hypoglycaemia
weight gain
avoid in pregnancy and breast feeding
4
Q
metformin
A
GI upset
lactic acidosis - liver or renal failure
CI; CKD tissue ischaemia - MI, sepsis contrast alcohol
if develop side effects - consider modified release
5
Q
pioglitazone
A
weight gain liver impairment fluid retention fractures bladder cancer
6
Q
enzyme inducers
A
PC BRAS phenytoin carbamazepine barbiturates rifampicin alcohol chronic sulphonylureas
7
Q
enzyme inhibitors
A
AO DEVICES allopurinol omeprazole disulfiram ethanol acute valproate isoniazid clarithromycin erythromycin sulphonamides
metronidazole
amiodarone
SSRIs
8
Q
steroids
A
STEROIDS stomach ulcers think skin edema right and left heart failure osteoporosis Infection diabetes syndrome - cushings
proximal muscle weakness
psychiatric - psychosis, insomnia
9
Q
NSAIDs
A
NSAIDS no urine - renal failure systolic dysfunction asthma Indigestion dyscrasia - clotting
10
Q
ACEi
A
cough
electrolytes
hypotension
11
Q
BB
A
hypotension
bradycardia
wheeze
worsens acute heart failure (improves chronic)
12
Q
CCB
A
hypotension
peripheral oedema
flushing
don’t combine verapamil with BB - bradycardia
13
Q
Diuretics
A
potassium
renal failure
14
Q
loop
A
gout
15
Q
K sparing
A
gynaecomastia
