Side Effects To Memorise

Question 1

Rifampicin

Answer 1

Orange tears/urine

Hepatitis

Question 2

Isoniazid

Answer 2

Neuropathy

Hepatitis

Question 3

Pyrazinamide

Answer 3

Hepatitis

Question 4

Ethambutol

Answer 4

Optic neuritis

Question 5

Phenytoin

Answer 5

Cerebellar syndrome, acne, coarse face, gum hypertrophy, hirsutism, inhibit COCP

Question 6

Carbamazepine

Answer 6

Rash, dizziness, hyponatraemia, hair thinning, inhibit COCP, agranulocytosis

Question 7

Sodium valproate

Answer 7

Tremor, weight gain, hair thinning, teratogenic

Question 8

Lamotrigine

Answer 8

Rash (Stevens-Johnson syndrome)

Question 9

SSRI

Answer 9

Fluoxetine, citalopram, sertraline

Nausea, low libido, withdrawal, insomnia, hyponatraemia

Question 10

TCA

Answer 10

Amitriptyline

Anti cholinergic, anti histaminergic, anti alpha adrenergic, hyponatraemia (SIADH), arrhythmia

Question 11

MOA Inhibitors

Answer 11

Selegiline

Hypertension, hepatocellular jaundice, hyperthermia

Question 12

ACE Inhibitors

Answer 12

Dry cough, postural hypotension, renal failure (renal artery stenosis), angioedema of the tongue, hyperkalaemia, profound hypotension when started

Check UE’s before and 2 weeks after starting

Question 13

Calcium channel blocker

Answer 13

Amlodipine, nifedipine, verapamil

Ankle oedema, headache, flushing, dizziness

Question 14

Beta blocker

Answer 14

Diabetes risk, impotence, bradycardia, fatigue, cold hands and feet, sleep disturbance

Question 15

Alpha blockers

Answer 15

Anti alpha adrenergic effects

Question 16

Diuretics

Answer 16

Dehydration, hypotension, hyperuricaemia, hypokalaemia (except K sparing eg. Epleronone, spironolactone), hyponatraemia, hypomagnesia

Question 17

Loop diuretics

Answer 17

Furosemide, bumetanide

Hypocalcaemia

Question 18

Thiazide diuretics

Answer 18

Indapamide, chlorothiazide

Hypercalcaemia

Question 19

Potassium sparring diuretics

Answer 19

Eplerenone, spironolactone

Hyperkalaemia, gynaecomastia

Question 20

Sulfalazine

Answer 20

DMARD

Myleosuppression, oligospermia, hepatitis, SJ syndrome, erythema nodosum, renal disorders, discoloured urine

Question 21

Chloroquine

Answer 21

DMARD

Retinopathy, tinnitus, myopathy

Question 22

Methotrexate

Answer 22

DMARD

Hepatic toxicity, pulmonary toxicity, myelosupression, mucositis

Question 23

TNF antagonists

Answer 23

DMARD

Infliximab, etanercept

Infusion reaction (including anaphylaxis), infections (TB reactivation), autoimmune reactions, blood disorders

Question 24

Cyclophosphamide

Answer 24

DMARD

Haemorrhagic cystitis, myelosupression, alopecia

Question 25

Insulin

Answer 25

Hypoglycaemia, fat hypertrophy at injection site, hypokalaemia, weight gain

Question 26

Metformin

Answer 26

Weight loss, lactic acidosis, metallic taste, GI disturbance, B12 deficiency

Question 27

Glicazide

Answer 27

Sulfonylurea Hypoglycaemia, weight gain

Question 28

Pioglitazone

Answer 28

Thiazolidinediones Fluid retention- heart failure and oedema, hepatotoxicity, fractures

Question 29

Sitagliptin

Answer 29

DPP4 Inhibitors Pancreatitis

Question 30

Empagliflozin

Answer 30

SGLT2 Inhibitors UTI, thrush, ketoacidosis, weight loss, may increase risk of amputation

Question 31

Antipsychotics

Answer 31

Anti dopaminergic, anti cholinergic, anti histaminegic, anti alpha adrenergic effects

Question 32

Clozapine

Answer 32

Agranulocytosis

Question 33

Chlorpromazine

Answer 33

Cholestatic jaundice

Question 34

Haloperidol

Answer 34

Prolonged QT interval, temperature dysregulation

Question 35

Lithium

Answer 35

Toxicity (tremor, ataxia, dysarthria), coma, convulsions, hypotension, diarrhoea, hypothyroidism, diabetes insipidus

Question 36

Steroids

Answer 36

Diabetes risk, Cushingoid appearance, psychosis, osteoporosis, hypokalaemia, hyperglycaemia, infections, leukocytosis, risk of a vascular necrosis

Question 37

Azathioprine

Answer 37

Myelosupression

Question 38

Cyclosporine

Answer 38

Immunosuppressant eg. RA tremor, interstitial nephritis, gum hyperplasia, burning in hands and feet, hypertrichosis (excessive body hair)

Question 39

Levodopa

Answer 39

Nausea, red urine, postural hypotension, dyskinesias, on off phenomena, wearing odd effects

Question 40

PPI

Answer 40

Omeprazole Tinnitus, GI disturbance, headache, hyponatraemia, hypomagnesia

Question 41

Amiodarone

Answer 41

Thyroiditis (hypo or hyper), pulmonary fibrosis, peripheral neuropathy, myopathy, grey skin, photosensitivity, hepatitis, metallic taste

Question 42

Digoxin toxicity

Answer 42

Xanthopsia (yellow/ orange tint to vision), GI distress, any arrhythmia

Question 43

Adenosine

Answer 43

Flushing, sense of impending doom

Question 44

Metoclopramide

Answer 44

Drug induced Parkinson’s | Galactorrhoea