signaling pathways of endocrine hormones Flashcards
(39 cards)
1
Q
FSH
A
cAMP
2
Q
LH
A
cAMP
3
Q
ACTH
A
cAMP
4
Q
TSH
A
cAMP
5
Q
CRH
A
cAMP
6
Q
hCG
A
cAMP
7
Q
ADH (V2 receptor)
A
cAMP
8
Q
MSH
A
cAMP
9
Q
PTH
A
cAMP
10
Q
calcitonin
A
cAMP
11
Q
GHRH
A
cAMP
12
Q
glucagon
A
cAMP
13
Q
histamine
A
cAMP (H2 receptor)
14
Q
BNP
A
cGMP
15
Q
ANP
A
cGMP
16
Q
EDRF
A
endothelium derived relaxing factor - eg NO- cGMP
17
Q
GnRH
A
IP3
18
Q
Oxytocin
A
IP3
19
Q
ADH (V1 receptor)
A
IP3- these are the receptors in blood vessels that are responsible for vasopressor action
20
Q
angiotensin II
A
IP3
21
Q
Gastrin
A
IP3
22
Q
Progesterone
A
intracellular receptor
23
Q
estrogen
A
intracellular receptor
24
Q
testosterone
A
intracellular receptor
25
cortisol
intracellular receptor
26
aldosterone
intracellular receptor
27
T3/T4
intracellular receptor
28
vitamin D
intracellular receptor
29
insulin
receptor tyrosine kinase. MAP kinase.
30
igf-1
receptor tyrosine kinase. MAP kinase.
31
fgf
receptor tyrosine kinase. MAP kinase. fibroblast growth factor. e.g.: in achondroplasia there is constitutive activation of FGFR3 actually inhibits chondrocyte proliferation.
32
pdgf
receptor tyrosine kinase- MAP kinase
33
egf
receptor tyrosine kinase- MAP kinase
34
prolactin
nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.
35
immunomodulators (IL2, IL6, IFN)
nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.
36
GH
nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.
37
G-CSF
nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.
38
EPO
nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.
39
thrombopoietin
nonreceptor tyrosine kinase. jak/stat pathway. acidophils and cytokines.
