Signaling Pathways (Table 14-2) Flashcards by Ashleigh Baan

Q

N1 nicotinic ACh agonists

A

nicotine, decamethonium

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Q

N2 nicotinic ACh agonist

A

nicotine, TMA

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Q

M1, M2, M3, M4, M5 muscarinic ACh agonists

A

muscarine

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Q

alpha1-adrenergic agonist

A

phenylephrine

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Q

alpha2-adrenergic agonist

A

clonidine

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Q

alpha1- and alpha2-adrenergic NE vs Epi

A

NE > or = Epi

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Q

beta1-adrenergic agonist

A

dobutamine, isoproterenol

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Q

beta2-adrenergic agonist

A

terbutaline, isoproterenol

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Q

beta3-adrenergic agonist

A

isoproterenol

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Q

beta1- beta2- and beta3-adrenergic NE vs Epi

A

Epi > NE

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Q

N1 nicotinic ACh antagonist

A

d-tubocurarine, alpha-bungarotoxin

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Q

N2 nicotinic ACh antagonist

A

hexamethonium

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Q

M1 muscarinic ACh antagonist

A

atropine, pirenzepine

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Q

M2 muscarinic ACh antagonist

A

atropine, methoctramine

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Q

alpha1-adrenergic antagonist

A

phentolamine

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Q

alpha2-adrenergic antagonist

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A

yohimbine

Q

beta1-adrenergic antagonist

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A

metoprolol

Q

beta2-adrenergic antagonist

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A

butoxamine

Q

beta3-adrenergic antagonist

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A

SR-59320A

Q

M1, M3, M5 muscarinic ACh G protein

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A

Galpha-q

Q

M2, M4 muscarinic ACh G protein

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A

Galpha-i, Galpha-o

Q

alpha1-adrenergic G protein

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A

Galpha-q

Q

alpha2-adrenergic G protein

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A

Galpha-i

Q

beta1- beta2- and beta3-adrenergic G protein

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A

Galpha-s

D1 G protein

Galpha-s

D2 G protein

Galpha-i

M1, M2, M3 muscarinic ACh linked enzymes

PLC

M2, M4 muscarinic ACh linked enzymes

adenyl cyclase

alpha1-adrenergic linked enzymes

PLC

alpha2-adrenergic linked enzyme

adenyl cyclase

beta1- beta2- and beta3-adrenergic linked enzyme

adenyl cyclase

D1, D2 linked enzyme

adenyl cyclase

M1, M3, M5 muscarinic ACh second messenger

IP3, DAG

M2, M4 muscarinic ACh second messenger

decreased intracellular cAMP concentrations

alpha1-adrenergic second messenger

IP3, DAG

alpha2-adrenergic second messenger

decreased intracellular cAMP concentrations

beta1- beta2- and beta3-adrenergic second messenger

increased intracellular cAMP concentrations

D1 second messenger

increased intracellular cAMP concentration

D2 second messenger

decreased intracellular cAMP concentration