Flashcards in Simmons Pharm 422 Exam 2 Deck (70)
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1
Conditions treated by Augmentin (first choice) (4)
Sinusitis
Impetigo
Cellulitis
Communication acquired pneumonia
Dog bite
SICC-DAWG!
2
Conditions treated with Amoxicillin First choice
(4)
Strep throat
Tonsillitis
Otitis media
Pharyngitis
STOP!
3
First choice antibiotic for meningitis
Ax to brain
Cefotaxime or Ceftriaxone
4
First line antibiotic C-diff
Metronidazole or Flagyl
5
Antibiotic for uncomplicated UTI in adult
Bactrim 3days or
Nitrofurantoin 7 days
6
First line antibiotic for MRSA
(The good witch)
Clindamycn
7
First line antibiotic treatment for Rickettsia, Lyme
Doxycycline
8
First line antibiotic treatment for pneumonia for mycoplasma
Azithromycin
9
First line antibiotic treatment for Community acquired pneumonia
Augmentin
10
First line antibiotic combo therapy for gonorrhea chlamydia infection
Ceftriaxone 250 mg IM
Azithromycin 1g ORAL
11
First line antibiotic treatment for pertussis
Azithromycin
12
Metronidazole (Flagyl) treats these two conditions
Bacterial vaginosis
C-diff
13
Antibiotics affecting protein synthesis
(Motl (y) crew
Macrolides
Oxazolidinones
Tetracyclines
Lincosamides
MOTLEY CREW
14
Antibiotics affect in Qt Prolongation
FM-am (3)
Fluoroquinolones
Macrolides
Anti-malarias
Amiodarone antipsychotics fluconazole
15
Drugs that affect G6PD
SAM CK
Sulfa drugs
aspirin
malaria drugs
high dose vitaminC
high-dose vitamin K
16
Methemoglobinemia (inducers)
Lidocaine spray and nitrates
17
Optional choices for impetigo or penicillin allergy
First second and third generation cephalosporins
Fluoroquinolones
18
Antibiotic treatment of UTI in pregnancy
Amoxicillin
19
Antibiotic used to treat UTI in children
Augmentin or cephalexin
20
Antibiotic treatment of UTI in geriatric
Bactrim
Levofloxacin
NO NITROFURANTOIN!
21
If allergy to amoxicillin what antibiotic will be used to treat strep throat?
Azithromycin
22
Which 2 antibiotics can cause C-diff infection?
The good witch
Brain biotics
Clindamycin and cephalosporins
23
Which two antibiotics absorption is impaired by dairy consumption
Tetracycline and Cipro
24
Which two antibiotics can cause peripheral neuropathy?
Nitrofurantoin
Zyvox
25
In regard to absorption and pregnancy which functions are increased?
Skin penetration
Gastric emptying
Lung absorption
26
In re: to absorption in pregnancy, which 3 functions are reduced?
GI Motility
gastric acid secretion
gastric acidity
27
Blood volume, total body water, and cardiac output are blank in pregnancy in regard to distribution?
Increased
28
Uterine blood flow, volume of distribution, and fat distribution are all blank pregnancy in regard to distribution?
Increased
29
What one function in regard to distribution is decreased in pregnancy?
Plasma protein binding
30
And pregnancy drugs that are excreted primarily by the kidneys show a blank in elimination?
Increase
31
During pregnancy we want to prescribe drugs that are what in terms of :
Protein
fat
Ionization status
molecular weight
Highly protein bound
Hydrophilic
Ionized
High molecular weight
32
Drugs to avoid during lactation
Chemotherapy
Lithium
Cyclosporin
Methotrexate
33
Are insulin and heparin OK for pregnancy?
Yes
34
Meds to avoid during pregnancy
NSAIDs
Coumadin
Aspirin
chemotherapy
Ace inhibitors
ARBS
35
Which antibiotics should be taken on an empty stomach
Levofloxacin
Macrolides
Penicillin
36
Flagyl should be taken with or without food?
With food
37
Myelosuppression
Serotonin syndrome
Peripheral neuropathy
Which antibiotic can cause all three?
Linezolid (Zyvox)
38
Penicillin, cephalosporins, glycopeptides All inhibitors of what?
Beta lacatamase
39
Lincosamides
Oxazoliddones
Macrolides
Tetracyclines
All affect what in bacteria?
Protein synthesis
40
Fluoroquinolones
Metronidazole
Most of these affect what in bacteria replication?
DNA GYRASE
41
Sulfonomides
Trimethoprim
Nitrofurantoin
All inhibit what in bacteria ?
Metabolic pathways
42
If spotting in follicular phase what adjustments need to be made in OCP?
More EE
43
Disulfiram reaction caused by these 2 antibiotics
Cephalosporins
Flagyl
44
Antibiotic used to tx syphilis and group A strep
Penecilin
45
6 conditions PCN treats
UUP SOS
URI, pharyngitis, sinusitis, OM, STI, UTI
46
In PCN script what will decrease dose?
low GFR
47
Ampicillin and Sulbactam
Augmentin
48
Weaken cell wall causing bacteria to absorb water and rupture
penicillin
49
CSF action w/inflammation (3/4th)
Cephalosporins
50
Which antibiotics are nephrotoxic?
Cephalosporins, Glycopetides (Vanco)
51
The antibiotic class that Inhibits folic acid synthesis
Sulfonamides (Trimethoprim) Bactrim
52
community acquired MRSA 1st & 2nd line
Bactrim first, Clindamycin second due to causing C-diff
53
Levofloxacin, ciprofloxacin, moxifloxacin belong to what class?
Flouroquinolones
54
Levofloxacin should be taken...?
on an empty stomach
55
Special (renal) considerations when dosing Flouroquinolones
- Decrease dose is CrCl <50
56
Antibiotic that has a metallic taste
Matronidazole (Flagyl)
Flouroquinolones
57
Pregnancy Cat C/D (avoid 3rd trimester),
Lactation: avoid
Peds: only >2y/o
Bactrim
58
Antibiotic that can cause kernicterus in babies
Bactrim
59
Which antibiotics can cause Photosensitivity?
Tetracyclines
Bactrim
Flouroquinolones
60
Linezolid Ex: Zyvox is in what class antibiotic?
Oxazalidinones
61
what antiobiotic treats these? VRE, MRSA, TB, group A/B strep
Oxazalidinones
Linezolid Ex: Zyvox
62
Tetracycline is which bacteriocidal or bacteriostatic?
bacteriostatic
63
h. pylori antiobiotics
Tetracycline, - Clarithromycin
64
Erythromycin, azithromycin, clarithromycin (Class)?
Macrolides
65
Glycopeptides example
Vancomycin / Televancin
66
Lincosamides
Ex: Clindamycin
67
Options for cellulitis
Augmentin
Clindamycin
68
Excellent activity against MSSA, strep, H. flu, M.
catarrhalis, Neisseria meningitides, E. coli, Klebsiella, etc.
aminopenicillins
69
• Ineffective against gram-negative anaerobes such as MRSA
PCN
70
