Simmons Pharm 422 Exam 2 Flashcards Preview

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Flashcards in Simmons Pharm 422 Exam 2 Deck (70)
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1

Conditions treated by Augmentin (first choice) (4)

Sinusitis
Impetigo
Cellulitis
Communication acquired pneumonia
Dog bite

SICC-DAWG!

2

Conditions treated with Amoxicillin First choice
(4)


Strep throat
Tonsillitis
Otitis media
Pharyngitis


STOP!

3

First choice antibiotic for meningitis

Ax to brain

Cefotaxime or Ceftriaxone

4

First line antibiotic C-diff

Metronidazole or Flagyl

5

Antibiotic for uncomplicated UTI in adult

Bactrim 3days or
Nitrofurantoin 7 days

6

First line antibiotic for MRSA

(The good witch)

Clindamycn

7

First line antibiotic treatment for Rickettsia, Lyme

Doxycycline

8

First line antibiotic treatment for pneumonia for mycoplasma

Azithromycin

9

First line antibiotic treatment for Community acquired pneumonia

Augmentin

10

First line antibiotic combo therapy for gonorrhea chlamydia infection

Ceftriaxone 250 mg IM
Azithromycin 1g ORAL

11

First line antibiotic treatment for pertussis

Azithromycin

12

Metronidazole (Flagyl) treats these two conditions

Bacterial vaginosis
C-diff

13

Antibiotics affecting protein synthesis

(Motl (y) crew

Macrolides
Oxazolidinones
Tetracyclines
Lincosamides

MOTLEY CREW

14

Antibiotics affect in Qt Prolongation


FM-am (3)

Fluoroquinolones
Macrolides
Anti-malarias
Amiodarone antipsychotics fluconazole

15

Drugs that affect G6PD

SAM CK

Sulfa drugs

aspirin

malaria drugs

high dose vitaminC

high-dose vitamin K

16

Methemoglobinemia (inducers)

Lidocaine spray and nitrates

17

Optional choices for impetigo or penicillin allergy

First second and third generation cephalosporins
Fluoroquinolones

18

Antibiotic treatment of UTI in pregnancy

Amoxicillin

19

Antibiotic used to treat UTI in children

Augmentin or cephalexin

20

Antibiotic treatment of UTI in geriatric

Bactrim
Levofloxacin

NO NITROFURANTOIN!

21

If allergy to amoxicillin what antibiotic will be used to treat strep throat?

Azithromycin

22

Which 2 antibiotics can cause C-diff infection?

The good witch
Brain biotics

Clindamycin and cephalosporins

23

Which two antibiotics absorption is impaired by dairy consumption

Tetracycline and Cipro

24

Which two antibiotics can cause peripheral neuropathy?

Nitrofurantoin
Zyvox

25

In regard to absorption and pregnancy which functions are increased?

Skin penetration
Gastric emptying
Lung absorption

26

In re: to absorption in pregnancy, which 3 functions are reduced?

GI Motility
gastric acid secretion
gastric acidity

27

Blood volume, total body water, and cardiac output are blank in pregnancy in regard to distribution?

Increased

28

Uterine blood flow, volume of distribution, and fat distribution are all blank pregnancy in regard to distribution?

Increased

29

What one function in regard to distribution is decreased in pregnancy?

Plasma protein binding

30

And pregnancy drugs that are excreted primarily by the kidneys show a blank in elimination?

Increase

31

During pregnancy we want to prescribe drugs that are what in terms of :
Protein
fat
Ionization status
molecular weight

Highly protein bound
Hydrophilic
Ionized
High molecular weight

32

Drugs to avoid during lactation

Chemotherapy
Lithium
Cyclosporin
Methotrexate

33

Are insulin and heparin OK for pregnancy?

Yes

34

Meds to avoid during pregnancy

NSAIDs
Coumadin
Aspirin
chemotherapy
Ace inhibitors
ARBS

35

Which antibiotics should be taken on an empty stomach

Levofloxacin
Macrolides
Penicillin

36

Flagyl should be taken with or without food?

With food

37

Myelosuppression
Serotonin syndrome
Peripheral neuropathy

Which antibiotic can cause all three?

Linezolid (Zyvox)

38

Penicillin, cephalosporins, glycopeptides All inhibitors of what?

Beta lacatamase

39

Lincosamides
Oxazoliddones
Macrolides
Tetracyclines

All affect what in bacteria?

Protein synthesis

40

Fluoroquinolones
Metronidazole

Most of these affect what in bacteria replication?

DNA GYRASE

41

Sulfonomides
Trimethoprim
Nitrofurantoin
All inhibit what in bacteria ?

Metabolic pathways

42

If spotting in follicular phase what adjustments need to be made in OCP?

More EE

43

Disulfiram reaction caused by these 2 antibiotics

Cephalosporins
Flagyl

44

Antibiotic used to tx syphilis and group A strep

Penecilin

45

6 conditions PCN treats

UUP SOS

URI, pharyngitis, sinusitis, OM, STI, UTI

46

In PCN script what will decrease dose?

low GFR

47

Ampicillin and Sulbactam

Augmentin

48

Weaken cell wall causing bacteria to absorb water and rupture

penicillin

49

CSF action w/inflammation (3/4th)

Cephalosporins

50

Which antibiotics are nephrotoxic?

Cephalosporins, Glycopetides (Vanco)

51

The antibiotic class that Inhibits folic acid synthesis

Sulfonamides (Trimethoprim) Bactrim

52

community acquired MRSA 1st & 2nd line

Bactrim first, Clindamycin second due to causing C-diff

53

Levofloxacin, ciprofloxacin, moxifloxacin belong to what class?

Flouroquinolones

54

Levofloxacin should be taken...?

on an empty stomach

55

Special (renal) considerations when dosing Flouroquinolones

- Decrease dose is CrCl <50

56

Antibiotic that has a metallic taste

Matronidazole (Flagyl)
Flouroquinolones

57

Pregnancy Cat C/D (avoid 3rd trimester),
Lactation: avoid
Peds: only >2y/o

Bactrim

58

Antibiotic that can cause kernicterus in babies

Bactrim

59

Which antibiotics can cause Photosensitivity?

Tetracyclines
Bactrim
Flouroquinolones

60

Linezolid Ex: Zyvox is in what class antibiotic?

Oxazalidinones

61

what antiobiotic treats these? VRE, MRSA, TB, group A/B strep

Oxazalidinones
Linezolid Ex: Zyvox

62

Tetracycline is which bacteriocidal or bacteriostatic?

bacteriostatic

63

h. pylori antiobiotics

Tetracycline, - Clarithromycin

64

Erythromycin, azithromycin, clarithromycin (Class)?

Macrolides

65

Glycopeptides example

Vancomycin / Televancin

66

Lincosamides

Ex: Clindamycin

67

Options for cellulitis

Augmentin
Clindamycin

68

Excellent activity against MSSA, strep, H. flu, M.
catarrhalis, Neisseria meningitides, E. coli, Klebsiella, etc.

aminopenicillins

69

• Ineffective against gram-negative anaerobes such as MRSA

PCN

70

? are the treatment of choice for mycoplasma pneumonia

Macrolides