Skeletal and Smooth Muscle Flashcards

(54 cards)

1
Q

What are the 3 types of joints?

A
  1. Fibrous
  2. Cartilaginous
  3. Synovial
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2
Q

What type of cartilage is a symphyses joint made of?

A

Fibrocartilage

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3
Q

What type of cartilage is a synchondrosis joint made of?

A

Hyaline cartilage

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4
Q

What are thin filaments made of?

A
  1. G-actin

2. F-actin

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5
Q

fetal structure which gives rise to the pulmonary trunk

A

conus arteriosis

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6
Q

Legamentum arteriosum is a remnant of the ____ ____

A

ductus arteriosus

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7
Q

Extrafusal fibers are _____ motor neurons

A

alpha

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8
Q

Intrafusal fibers are ____ motor neurons

A

gamma

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9
Q

What two types of sensors are within the muscle spindle?

A
  1. nuclear chain fibers

2. nuclear bag fibers

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10
Q

What do muscle spindles do?

A

sense rate of stretch in the deep tendon reflex

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11
Q

What are Type I fibers?

A

Slow twitch muscles. Endurance. Small diameter. Aerobic respiration. Resist fatigue. Low stores of glycogen.

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12
Q

What are Type IIa fibers?

A

Intermediate twitch muscles

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13
Q

What are Type IIb fibers?

A

Fast twitch fibers.

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14
Q

Type I fibers are red due to _______

A

high amount of myoglobin

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15
Q

Type IIb fibers are white due to ______

A

lack of myoglobin content

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16
Q

Reflex circuitry is located ______

A

exclusively in the spinal cord

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17
Q

Actin and myosin overlap in smooth muscle, giving rise to a ______ _______

A

Dense Body

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18
Q

What are the two noncontractile intermediate filaments located in smooth muscle?

A

Desmin and Vimentin

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19
Q

How many calcium molecules bind to calmodulin in contraction?

A

4

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20
Q

Define extensibility

A

Ability of a muscle to stretch to its normal resting length and beyond

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21
Q

Elasticity

A

ability of a muscle to recoil back to its original length after being stretched

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22
Q

What are satellite cells?

A

stem cells under skeletal muscle basement membrane

23
Q

Darker bands in a muscle are __ bands. The lighter bands are __ bands.

A

Dark - A bands

Light - I bands

24
Q

What is the largest protein known?

25
What binds to the Z and M lines of a muscle?
Titin
26
Where is Dystrophin found?
Just inside the sarcolmma
27
Dystrophin transfers force from the contractile system to the outside of the cells via membrane-spanning proteins called _______
Integrins
28
How do muscle shorten during contraction?
Actin slides over myosin
29
Troponin-tropomyosin complex regulates contraction in response to ____
calcium
30
Thin filaments are composed of ____, _____, and _____
actin, troponin, and tropomyosin
31
How is the myosin head dislodged from actin after the power stroke?
ATP
32
Why does rigor mortis occur?
the muscles are unable to relax due to lack of ATP following death
33
When can optimal force from a muscle can be produced?
From rest
34
High levels of troponin in the blood can indicate what? (2 things)
1. heart attack | 2. recent exercise
35
What is a motor endplate?
Where a motor neuron synapses on the sarcolemma
36
The infoldings of a motor endplate are lined with ______
ACh receptors
37
What is the purpose of T-Tubules?
to bring stimulation/signal from a motor unit deep inside a muscle cell so all sarcomeres can be contracted
38
Depolarization wave goes all the way down the T-tubles to the _______ channels
L-Type Ca2+ channels
39
L-Type Ca2+ channels are mechanically coupled to _____ channels, which release Ca2+ from the sarcoplasmic reticulum to the cytoplasm
Ryanodine channels
40
Ca2+ binds to subunit on _____, hich reveals the binding site for myosin
troponin
41
Botulinum toxin interferes with _____ release
ACh
42
How does Curare cause paralysis?
binds/blocks ACh receptors
43
What is Myasthenia gravis?
Paralysis from antibodies blocking ACh from reaching muscle fibers
44
What is a possible treatment for Myasthenia gravis?
Eserine
45
Does the heart undergo temporal summation of twitches from individual action potentials?
FUCK NO! only skeletal muscle does that shit
46
What is Tetanus?
a sustained contraction in skeletal muscle
47
What is the difference between Isometric and Isotonic contraction?
Isometric - muscle is stimulated but *doesn't move* | Isotonic - muscle shortens with stimulation
48
What is creatine phosphate?
Energy source/protein present in muscle
49
Once creatine phosphate is drained, how does the muscle use energy?
1. Anaerobic respiration - buildup of lactic acid | 2. Aerobic respiration - needs oxygen. Produces more ATP than anaerobic
50
What is the difference between visceral and multiunit smooth muscle?
visceral - functional unit that works through gap junctions | multiunit - individual nerve endings to individual muscle fibers
51
Smooth muscle cell margins contain _____
caveolae
52
Smooth muscle has small indentations of _____ _____ instead of receptor mediated endocytosis
pinocytotic vesicles
53
Contraction is mediated by _____ ______ _____
Myosin Filmanet Proteins
54
Relaxation is mediated by ____ _____ ______
Myosin Light Chain Phosphatase