Skeletal Muscle Structure & Function Flashcards

1
Q

What are the 3 types of muscle?

A

Striated = skeletal and cardiac. Non-striated = smooth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Outline the features of skeletal muscle

A

Multinucleated, fused cells, attached skeleton, voluntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe cardiac muscle

A

Branched uninucleated, heart only, intercalated disks, involuntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Outline the characteristics of smooth muscle

A

Distinct cells, spindle shaped, wall of internal organs, involuntary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Define fasciculation

A

Small local involuntary muscle contractions and relaxation – may be visible under skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe the structure, function and placement of circular muscles

A

Concentric fibres, act as sphincter to adjust opening, attach to skin/ligaments and fascia rather than bone e.g. orbicularis occuli/oris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the 3 main categories of parallel muscles?

A

Strap, fusiform, fan shaped

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe a parallel strap muscle

A

Shape = belt, fibres run longitudinally to contraction direction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Outline a parallel fusiform muscle

A

Shape = wider in the centre, taper off at the ends

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is a parallel fan shaped muscle?

A

Shape = fibres converge at one end and spread over broad area at other end

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the 3 types of pennate muscle and what distinguishes them?

A

Unipennate = all fascicles on same side as tendon.

Bipennate = fascicles on both sides of central tendon.

Multipennate = central tendon branches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the difference between a muscle origin and insertion?

A

Origin = greater mass and more stable during contraction. Insertion = tends to be moved by contraction, tends to be distal, may be bone/tendon/CT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is compartment syndrome?

A

Trauma in one compartment (limbs divided into sections by fascia) = internal bleeding which exerts pressure on blood vessels and nerves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What role can a muscle assume in movement?

A

Agonist, antagonist, synergist (assists), neutralisers (prevents unwanted), fixator (hold part immobile)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Describe an isotonic contraction

A

Constant tension, variable muscle length: 1) concentric = shortens 2) eccentric = extended

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Outline an isometric contraction

A

Constant length, variable tension

17
Q

What is a first/second/third class lever?

A

First = load and effort on either side of the fulcrum (see-saw).

Second = load and effort on the same side, effort is furthest away (wheelbarrow).

Third = load and effort on the same side, load is furthest away (fishing-rod)

18
Q

What is rigor mortis?

A

ATP depleted, myosin heads can’t detach

19
Q

How any motor neurons innervate a single muscle fibre?

20
Q

How many muscles fibres can a motor neuron innervate?

21
Q

What are the 3 main muscle fibre types?

A

Slow oxidative type I (many mitochondria),

fast oxidative type IIA (many mitochondria),

fast oxidative type IIX

22
Q

What is the name given to sensory receptors located in intrafusal muscle fibres that detect change?

A

Proprioceptors

23
Q

How is muscle force controlled?

A

Rate code = more AP the more force. Size = small motor neurons recruited before large

24
Q

How is baseline tone maintained?

A

Healthy muscle never fully relaxed = retain tension and stiffness = tone

25
What is hypotonia?
Lack of skeletal muscle tone – symptom rather than a condition e.g. muscular dystrophies
26
Besides K+ leak channels, skeletal muscles fibres also have high conc of?
Cl- leak channels
27
What is myotonia?
Inability to relax muscle at will caused by mutations to chloride channel CLCN1, recessive or dominant
28
In skeletal muscle which ion provides the most conductance?
Cl-
29
What are the sources of ATP in muscle?
Short term stores ATP, creatine phosphate, glycolysis, oxidative phosphorylation
30
What causes acidosis?
Current thinking is that acidosis is not caused by lactate but other reactions like ATP hydrolysis