Flashcards in Sketchy - Macrolides Deck (11):
What is first line treatment for infection with Bordatella pertussis?
Close contacts need prophylaxis
CAP by what bugs can effectivey be treated with macrolides?
Strep pneumo, H. flu, Moraxella
Use what macrolide for atypical (walking) pneumonia as caused by Mycoplasma, Chlamydia and Legionella?
Besides doxycycline, what antibiotic is effective for urethritis and cervicitis caused by Chlamydia?
Clinical use in neonates: Erythromycin
Neonatal conjunctivitis and pneumonia caused by Chlamydia trach;
Neonatal conjunctivitis caused by Nesseria gonorrheae
Azithromycin is indicated for what zoonotic disease?
Cat scratch fever - Bartonella henselae
What is recommended treatment for Mycobacterium avium?
Macrolides - both azithromycin and clarithromycin
Adverse effects: Macrolides
Acute cholestatic hepatitis --> jaundice;
Torsades strip, prolonged QT syndrome;
cytochrome P450 inhibition