Skin

Question 1

IgG against desmoglein (autoimmune destruction of desmosomes)… blisters on skin and oral mucosa

Answer 1

pemphigus vulgaris

Question 2

what kind of blisters in pemphigus vulgaris

Answer 2

suprabasal in the stratum spinosum (where desmosomes are)

Question 3

excessive keratinocyte prolif leads to neutrophils in corneum… salmon plaques with silver scales and auspitz sign

Answer 3

psoriasis

Question 4

kyperkeratosis in male with family history of males having this condition… thin stratum granulosum

Answer 4

ichythosis vulgaris

Question 5

very young child with blisters that separate the basal layer from the basement membrane without antibodies or inflammation

Answer 5

epidermolysis bullosa

Question 6

itchy rash and bullae with IgG antibasement membrane antibodies (against the hemidesmosomes)

Answer 6

Bullous Pemphigoid

Question 7

IgA against gluten deposited at tips of dermal papillae

Answer 7

dermatitis herpetiformis

Question 8

associated with infection or drug rxn, presents as target papules that have central bullae with surround erythema

Answer 8

erythema multiforme

Question 9

erythema multiforme with fever and oral mucosa/lip involvement

Answer 9

Stevens-Johnson syndrome

skin sloughs off

Question 10

itchy planar purple papules with reticular white lines on oral mucosa… inflammation at dermal-epidermal junction assoc with chronic hep c

Answer 10

lichen planus

Question 11

poison ivy

Answer 11

allergic contact dermatitis - oozing rash that is itchy

Question 12

stiff skin on fingers with abundant collagen bundles

Answer 12

scleroderma

Question 13

papule associated with pilosebaceaous unit and proprionobacteria

Answer 13

acne vulgaris

Question 14

localized benign neoplastic prolif of melanocytes within epidermis or dermis

Answer 14

nevus (mole)

dysplastic would be risk marker for melanoma

Question 15

prognosis for malig melanoma?

Answer 15

depth of invasion

Question 16

benign squamous prolif that is easily rubbed off (looks like waxy stuck on)

Answer 16

suborrheic keratosis

Question 17

what can suborrheic keratosis signal?

Answer 17

GI malignancy

Question 18

locally invasive epidermal neoplasm extending from epidermis into papillary dermis… pink, pearl like assoc with upper lip

Answer 18

basal cell carcinoma

Question 19

malig keratin perals that appear as raised plaques, can be assoc with lower lip or back.shoulders.face

Answer 19

squamous cell carcinoma

Question 20

precursor for squamous cell carcinoma

Answer 20

actinic keratosis

scaly hyperkeratotic on face/back/neck