Skin

Question 1

What are the functions of the skin

Answer 1

Protection against injury and pathogens

Waterproofing and fluid conservation

Thermoregulation - sweat and blood flow variation

Grip

Sensory organ

Question 2

HOw thermoregualtion?

Answer 2

Plexuses - can fill area w blood

Question 3

Outline the structure of the skin

Answer 3

Epidermis

Dermis

Subcutis

Question 4

What does the epidermis consist of?

Answer 4

Stratum Corneum

• corneocytes, anuclear
• protective

Stratum Granulosum

Straum Spinosum

• keratin producing epidermal cells
• desmosomes

Stratum Basale

• Basal cells for BM connection
• keratinocytes

Stratum Lucidum

Question 5

What does the dermis consist of?

Answer 5

Supportive connective tissue amtrix

• Collagen 70pc, elastin GAGs
• Fibroblasts
• Immune cells
• Blood vessels

Question 6

HOw is keratin made

Answer 6

Basal cell forms prickle cell which forms granular cell which becomes keratin

Question 7

How is the dermo-epidermal junction maintained?

Answer 7

Hemidesmosomes
- anchoring fibrils and filaments

Problem leads to epidermolysis bullos

Question 8

How are melanocytes developed? Wher are they and WHJQAT DO THEWY DO

Answer 8

ORIGINATE FROM NEURAL CREST
Surround kerationcyte in STRATUM BASALE
MAke melanin - EU and PHAEOmelanin