Skin and Sensory Receptors Flashcards
(45 cards)
epidermis
outer epithelial layer
protection
basal layers fold to dermal papillae
4/5 layers
dermis
underlying connective tissue
thick, sensation, protection, thermal reg, nerves, blood supply
superficial fascia / hypodermis / subcutis
deep to the dermis is loose connective tissue
adipose
some skin appendages may reach it
thin skin has:
hair follicles
thick skin is:
glabrous - non-hairy, no sebaceous or apocrine glands)
epithelium of epidermis
keratinised, stratified, squamous epithelium
layers of skin from deep to superficial
stratum basale spinosum (prickle cell) granulosum (granular) lucidem corneum (keratin layer)
stratum basale
responsible for constant regeneration
single layer
stratum spinosum
lots of desmosomes which anchor cells to each other
thick tufts of intermediate filament (keratin)
stratum granulosum
lose nuclei and cytoplasmic organelles
keratinisation
lipid rich secretions which act as water sealant
stratum lucidem
thin transparent layer
stratum corneum
layer of dead cells
flattened squames filled with keratin
which layer is absent from thin skin?
stratum lucidem
3 non-epithelial cells
melanocytes
langerhans cells
merkel cells
melanocytes
pigment for skin
langerhans cells
immunological role
merkel cells
mechanoreceptors
basal cell carcinoma affects which layer
basal layer
squamous cell carcinoma affects which layer
granular/keratin layer
malignant melanoma affects which layer
melanocytes in basal layer
which is worst cancer to get?
malignant melanoma
what are warts?
small rough lumps
HPV infection
underlying dermis and hypodermis
features absent from thick skin
hair
sebaceous glands
apocrine sweat glands
involved in development of acne
sebaceous glands produce excess sebum