Skin and Sensory Receptors Flashcards

(45 cards)

1
Q

epidermis

A

outer epithelial layer

protection
basal layers fold to dermal papillae
4/5 layers

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2
Q

dermis

A

underlying connective tissue

thick, sensation, protection, thermal reg, nerves, blood supply

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3
Q

superficial fascia / hypodermis / subcutis

A

deep to the dermis is loose connective tissue
adipose
some skin appendages may reach it

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4
Q

thin skin has:

A

hair follicles

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5
Q

thick skin is:

A

glabrous - non-hairy, no sebaceous or apocrine glands)

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6
Q

epithelium of epidermis

A

keratinised, stratified, squamous epithelium

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7
Q

layers of skin from deep to superficial

A
stratum basale
spinosum (prickle cell)
granulosum (granular)
lucidem 
corneum (keratin layer)
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8
Q

stratum basale

A

responsible for constant regeneration

single layer

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9
Q

stratum spinosum

A

lots of desmosomes which anchor cells to each other

thick tufts of intermediate filament (keratin)

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10
Q

stratum granulosum

A

lose nuclei and cytoplasmic organelles
keratinisation
lipid rich secretions which act as water sealant

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11
Q

stratum lucidem

A

thin transparent layer

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12
Q

stratum corneum

A

layer of dead cells

flattened squames filled with keratin

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13
Q

which layer is absent from thin skin?

A

stratum lucidem

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14
Q

3 non-epithelial cells

A

melanocytes
langerhans cells
merkel cells

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15
Q

melanocytes

A

pigment for skin

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16
Q

langerhans cells

A

immunological role

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17
Q

merkel cells

A

mechanoreceptors

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18
Q

basal cell carcinoma affects which layer

A

basal layer

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19
Q

squamous cell carcinoma affects which layer

A

granular/keratin layer

20
Q

malignant melanoma affects which layer

A

melanocytes in basal layer

21
Q

which is worst cancer to get?

A

malignant melanoma

22
Q

what are warts?

A

small rough lumps
HPV infection
underlying dermis and hypodermis

23
Q

features absent from thick skin

A

hair
sebaceous glands
apocrine sweat glands

24
Q

involved in development of acne

A

sebaceous glands produce excess sebum

25
what are hair follicles?
long thin cylinderical shaft composed of keratin and arranged in an organised manner function: thermoreg
26
what are sebaceous glands?
secrete sebum into hair follicle provide waterproofing
27
what are eccrine glands?
throughout skin synthesise thin watery liquid evaporation of sweat reduces body temp
28
what are apocrine glands?
mainly in axilary and groin regions no definite function animal scent production
29
what are erector pili muscles?
small smooth muscle bindles attached to hair follicles below sebaceous gland contraction = hair stands up standing up traps air = insulation contraction can force sebum up protecting hair
30
what is supplied sympathetically?
arrector pilli eccrine (merocrine) - not attached to hair follicle vessels - sym = contraction
31
dermis is split into what layers
papillary | reticular
32
papillary layer
superficial, loosely woven
33
reticular layer
deeper, thicker, denser layer
34
the epidermis and dermis interdigiate forming:
epidermal downgrowths: rete ridges | epidermal upgrowths: dermal papillae
35
first degree burns
only epidermis
36
second degree burns
epidermis and dermis
37
third degree burns
all layers of the skin, epidermis, dermis, hypodermis
38
what is a dermotome?
area of skin supplied by a single spinal nerve
39
two sub groups of cutaneous sensory receptors
free nerve endings | encapsulated nerve endings
40
free nerve ending functions
nocireceptors thermoreceptors mechanoreceptors some associated with Merkel cells - basal layer Merkel cell-neurite complexes act as mechanoreceptors to respond to pressure
41
encapsulated nerve endings
mechanoreceptors - meissners, pacinian, ruffiani
42
merkel cell-neurite complex
basal layer epidermis slow sustained touch/pressure
43
pacinian corpuscle
deep in hypodermis -sole of feet deep pressure or rapid vibration rapid
44
meissner's corpuscle
dermal papillae of skin - fingertips, nipples, eyelids rapid changes in texture, pressure and vibration
45
ruffini
dermis layer slow stretching, sheering