Skin and Soft Tissue Infections Flashcards

(27 cards)

1
Q

List 6 types of infections commonly caused by water exposure.

A
Aeromonas
Edwardsiella tarda
Erysipelothrix rhusiopathiae
Vibrio vulnificus 
Mycobacterium marinarum
Vibrio parahaemolyticus
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2
Q

Define cellulitis.

A

Infection of the deeper dermis and fat layers after bacteria breach the skin barrier

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3
Q

What are the most common causes of cellulitis? (2)

A

Staph. aureus

Beta haemolytic streptococci, e.g.
-Strep. pyogenes

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4
Q

Describe the clinical features of cellulitis. (5)

What is the cellulitis triad? (3)

A

CELLULITIS TRIAD:
Oedema
Erythema
Warmth

OTHER FEATURES:
Skin changes
Fever

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5
Q

List 6 differential diagnoses for cellulitis.

A
Stasis dermatitis
Acute arthritis
Pyoderma gangrenosum
Hypersensitivity/drug reactions
DVT
Necrotising fasciitis
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6
Q

List 4 general risk factors for cellulitis.

List 8 local risk factors for cellulitis.

A
GENERAL RISK FACTORS:
Venous insufficiency
Lymphoedema
Pregnancy
White Caucasian
LOCAL RISK FACTORS:
Ulcers
Eczema
Athlete's foot
Burns
Surgical wounds
IVDUs
Trauma
Tattoos
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7
Q

Describe the classification of cellulitis.

HINT: there are 4 classes.

A

CLASS 1:
No sepsis
No co-morbidities

CLASS 2:
Possible systemic illness
At least one of:
-Peripheral vascular disease
-Obesity
-Venous insufficiency

CLASS 3:
Significant systemic illness
Unstable co-morbidities

CLASS 4:
Sepsis
Necrotising fasciitis
Unstable co-morbidities

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8
Q

In cellulitis, what can cause failure to respond to antibiotics? (3)

A
Resistant organisms (e.g. MRSA)
Underlying conditions (e.g. bone infection, abscess)
Incorrect diagnosis
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9
Q

When would you consider hospital admission in cellulitis patients? (4)

A

Severe, localised pain

Rapidly evolving skin lesions

SIRS:

  • HR 100+
  • RR 20+
  • Temp <36 or 38+
  • WCC <4 or 12+

Sepsis:

  • SIRS
  • Organ dysfunction (confusion, hypotension or RR 22+)
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10
Q

How would you treat cellulitis? Consider:

a) Mild cellulitis
b) Moderate cellulitis
c) Severe cellulitis

A

MILD CELLULITIS:
Flucloxacillin (oral)
-Duration: 7 days

MODERATE CELLULITIS:
Flucloxacillin (oral)
-Duration: 10 days

SEVERE CELLULITIS:
Flucloxacillin (IV)
Gentamicin (IV)
Clindamycin (IV)
-Duration: 10 days
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11
Q

Define erysipelas.

A

Infection of the upper dermis and superficial lymphatics in the skin

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12
Q

Define impetigo.

A

Superficial bacterial infection of the skin

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13
Q

Define necrotising fasciitis.

A

Severe inflammation and infection of the muscle sheath that leads to necrosis of the subcutaneous tissue and adjacent fascia

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14
Q

Define tinea.

A

A superficial dermatophyte infection of the epidermis, characterised by scaly, inflammatory or non-inflammatory patches

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15
Q

Define dermatophyte.

A

A pathogenic fungus that grows on skin, mucous membranes, hair, nails and other body surfaces

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16
Q

What are 2 other names for erythema infectiosum?

Define this disease.

A

Fifth disease, slapped cheek syndrome

A common, benign infection in children, caused by human parvovirus B19

17
Q

What is erysipelas caused by?

A

Group A streptococci (strep. pyogenes)

18
Q

Describe the clinical features of erysipelas.

A

Raised lesion
Clear line of demarcation
Elevated ASOT (antistreptococcal antibody titres)

Distribution:

  • Butterfly distribution in face (20%)
  • May involve the ear (cellulitis does not)
  • Legs (80%)
19
Q

How would you treat erysipelas?

A

Flucloxacillin or amoxicillin

PLUS

Gentamicin

20
Q

What is impetigo caused by? (4)

A

Primary infection:

  • Staph. aureus
  • Other staphylococci
  • Streptococci

Secondary infection:
-Herpes simplex virus

21
Q

Describe the initial features of necrotising fasciitis. (5)

Describe the later features of necrotising fasciitis.

A
INITIAL FEATURES:
Severe and out of proportion pain
Rapid spread
Systemically unwell patient
Erythema and swelling
No well-defined margins
LATER FEATURES:
Colour change: red/purple to blue/grey
Bullae development
Anaesthesia
Dusky skin
Necrosis
Skin crepitus 
Complete tissue destruction
22
Q

Which 5 antibiotics would you give for necrotising fasciitis?

A
Flucloxacillin IV
Benzylpenicillin IV
Gentamicin IV
Clindamycin IV
Metronidazole IV
23
Q

What organism most commonly infects animal bites?

24
Q

Which organisms can cause tinea? (3)

Which is the most common?

A

Most common: trichophyton

Other causes:

  • Microsporum
  • Epidermophyton
25
What causes erythema infectiosum?
Human parvovirus B19
26
What causes hand, foot and mouth disease?
Coxsackie virus A16
27
What is scalded skin syndrome also called? What causes it?
Ritter's disease; pemphigus neonatorum Staph. aureus