Skin Infections Flashcards

1
Q

Successful establishment of infection by bacterial pathogens depend on…

A

Adhesion to host cells

  • Specialised pili/fimbriae
  • Cell wall/capsule
  • Adhesins

Secretory mechanisms
- export/deliver toxins, enzymes, invasions (invasion, spread, acquire nutrients)

Motility/Chemotaxis
- spread to new sites + communicate with each other

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2
Q

Adherence

A

Attachment needed to avoid being swept away favourable environment/niche

GIT, lungs, UT

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3
Q

Colonisation

A

Requires active replication + persistence at specific site

Site of attachment + colonisation linked with tissue tropism/site predilection -able to recognise/bind host receptors

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