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Flashcards in Skin manifestations Deck (20):
1

Describe erythema nodosum

Painful raised lesions on shins bilaterally

2

Causes of erythema nodosum

NO cause
Drugs - sulphonamides, penicillin
Oral contraceptive pill
Sarcoidosis
UC and chron's
Microbiology - mycobacterium tuberculosis and group A beta haemolytic streptococci

3

Describe erythema multiforme

Target lesions on palms, soles and limbs

4

Describe Stevens-Johnson syndrome

Severe variant of erythema multiforme with fever and mucosal involvement
Due to hypersensitivity reaction to drugs - NSAIDs, allopurinol and antiepileptics

5

Describe erythema migrans

Initial small papule at site of tick bite
Develops into large erythematous ring with central fading lasting up to 3 months
LYME DISEASE

6

Describe erythema marginatum

Pink coalescent rings on trunk that come and go
Seen in rheumatic fever

7

Describe pyoderma gangrenosum

Nodulo-pustular ulcer
~10cm
Necrotic edge
Purulent surface

8

What is pyoderma gangrenosum associated with

IBD
Wegeners granulomatosis

9

Treatment for pyoderma gangrenosum

Oral steroids and Ciclosporin

10

What exacerbates vitiligo

Sunlight makes it itchy

11

Skin changes in chron's

Ulcers
Erythema nodosum
Pyoderma gangrenosum

12

Skin changes in diabetes mellitus

Ulcers
Acanthosis nigricans (type 2 - insulin resistance)

13

Skin changes in dermatomyositis

Shawl sign
Heliotrope rash on eyelids
Grotton's papules

14

Skin changes in coeliac disease

Dermatitis herpetiformis - itchy blisters on knees, elbows and scalp

15

Treatment for dermatitis herpetiformis

Responds to dapsone within 48 hours

16

Skin changes in hyperthyroidism

Pretibial myxoedema - red, oedematous swelling above lateral malleolus

17

Skin changes in chronic liver disease

Palmar erythema
Koilonychia
Leukonychia
Spider naevi
Gynaecomastia
Jaundice
Bruising
Scratch marks
Loss of male hair distribution

18

Skin changes in malabsorption

Dry skin
Hyperpigmentation
Hair loss

19

Describe acanthosis nigricans

Hyperpigmentation in areas of skin folds e.g back of neck and axilla

20

Causes of acanthosis nigricans

Insulin resistance (DM type 2, acromegaly, PCOS)
Gastric cancer