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HIV > Skin Manifestations and Malignancies of HIV > Flashcards

Skin Manifestations and Malignancies of HIV Flashcards

1
Q

Features of seborrhoeic dermatitis

A

eczematous skin reaction to melasezzia furfur typically affecting scalp, nasal creases, eyebrows and chest

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2
Q

Features of KS (3)

A

HHV-8

purplish-red nodules

cutaneous lesions affect face, oral cavity and perineum

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3
Q

Features of nodular prurigo

A

red papules>chronic nodules

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4
Q

areas affected by molluscum (2)

A

seen extragenitally in immunocompromised

esp. in bearded area

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5
Q

Opportunistic fungal infections in HIV (3)

A

penicillium marnefi

cryptococcus neoformans

histoplasma capsulatum

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6
Q

All skin manifestations of HIV (14)

A

seborrhoeic dermatitis

KS

eosinophilic folliculitis

non-specific pruritus

nodular prurigo

drug rashes

HPV

molluscum

HSV

candidiasis

tinea

scabies

syphilis

opportunistic fungal infections

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7
Q

AIDS-defining malignancies

A

high-grade B-cell NHL (including AIDS-related primary cerebral lymphoma)

KS

invasive cervical ca.

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8
Q

Other AIDS-related malignancies (4)

A

HPV-driven

KSHV

EBV

other: seminoma, lung ca.

(NB incidence of all ca. increased in HIV)

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9
Q

HPV-driven ca, (4)

A

cervical

anal

VIN

head and neck ca.

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10
Q

Features of KSHV infection (2)

A

KS

Castleman’s:

  • hepatosplenomegaly
  • lymphadenopathy
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11
Q

Features of EBV infection (3)

A

NHL

PCL

Hodgkin’s

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12
Q

Subtypes of systemic lymphoma (2)

A

2/3 Burkitt’s

1/3 diffuse large cell

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13
Q

Presentation of systemic lymphoma (3)

A

nodal disease

GI disease

effusions

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14
Q

Rx of systemic lymphoma

A

chemo+cART

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15
Q

Features and prognosis of PCL

A

NHL confined to cranio-spinal axis w/o systemic involvement

poor prognosis

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16
Q

CT/MRI findings of PCL

A

ring-enhancing lesions w. prominent mass effect and oedema

17
Q

DDx of PCL and differentiating features (5)

A

toxoplasmosis

differentiating features of PCL:

  • periventricular ring-enhancing lesions
  • slower onset
  • no fever
  • EBV on CSF PCR
18
Q

Rx of PCL

A

whole brain irradiation, commence cART

19
Q

Presentation of KS (4)

A

multiple, raised, pigmented, non-blanching lesions

PAINLESS

can get nodular lesions in oral cavity

can get visceral KS affecting lungs and stomach

(caused by HHV-8)

20
Q

Rx of KS

A

should regress w. cART

local chemo/RT for cosmetic reasons

HIV (7 decks)

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