Skin temperature and control Flashcards

1
Q

What does homeothermic mean?

A

We regulate our own body’s temparature

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2
Q

hOW MUCH CAN BODY TEMPERTURE DROP IN DEEP SLEPE?

A

1 ‘C

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3
Q

How much head production to we make at rest? Onn a brisk walk?

A

80kcal/hour
600kcal/hour

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4
Q

How do we lose heat?

A

Convection
Conduction
Evaporation (resp +sweating, 600ml/day at rest, 4L/hr at extremes)
Radiation (60% heat loss)

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5
Q

Cold receptor peak firing rte

A

25’C

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6
Q

Warm receptor peak firing ratw

A

40’C

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7
Q

Where are erhiperhal thermo receptors?

A

Skin (esp face and scrotum)

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8
Q

WHere ar ecentral thermo receptors?

A

Spinal chord, abdo. organs, hypothalmus

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9
Q

What does the Hypothalmus do?

A

Takes in all the information and decides what to do with it! (from perioheral and central chemoreceptors)

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10
Q

How do we respond to cold stress

A

General metabolism (from not 100% efficient processes)
Voluntary muscular activity (“Futile” activity)
Shivering thermogenesis
Non-shivering thermogenesis (brown adipose tissue in infants)

Arteriorlar constriction
Add clothing, move to a warmer area, reduce surface area

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11
Q

What degree cut off arfor hypothermia?

A

35’C

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12
Q

What are the cellular and vsacular complications of cold stress?

A

Vascular:
-Vasoconstriction +increased viscosity of blood, promotes thrombosis
-anoxia
-death

Cellular:
-ice forms in extracellular space,
-osmotic gradient
-cell dehydration and death

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13
Q

Excess winter mortalilty in the UK. Why?

A

40%

Colds, flu

Also increased MI and strokes due to colder temps and increasde viscosity of blood and increased vasoconstriction etc

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14
Q

What temps for heat exhaustion?Heat stroke signs

A

37.5-40’C:
vasodilation -> drop in central blood volume
fluid/salt inbalance due to excess sweating
-headache, confusion, nausea, sweating, clammy skin, tachycardia, hypotension, weak pulse, fainting, collapse

Heat stroke = over 40’C
Body’s control mechanisms fail, hot DRY skin, circilatory collapse

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15
Q

Whiat causes fever?

A

endogenous pyrogens - IL1 IL6 to hyperthalmus and increases “set point “ above 37’C.

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16
Q

How do aspirin and paracetamol work as antipyretics

A

WHen set point has shifted, hypothalus produces prostaglandins by enzyme cyclo-oxygenase to increase the temperature.. They act by inhibiting this enzyme.