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Head And Neck Radiology > Skull Base > Flashcards

Flashcards in Skull Base Deck (4)
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1

What is a chordoma?

Neoplasm arising from the remnants of the notochord which presents as a destructive midline mass.
Most common locations: sacrum (50%), clivus (35%), vertebral bodies (most commonly C2).
Typically it is T2 bright and has a predilection for the spheno-occipital synchondrosis.
Main differential is chondrosarcoma.

2

Chondrosarcoma features.

1. Almost always just lateral to the midline
2. T2 bright but will have classic “arcs and rings” matrix on CT

3

What skull changes do you see in Paget’s?

1. Osteolysis circumscripta - large areas of osteolysis in the frontal and occipital bones in lytic phase
2. “Cotton wool” appearance in mixed phase
3. Thickened and expanded in sclerotic phase.

4

Skull base lesion differential.

1. Chordoma
2. Chondrosarcoma
3. Metastasis
4. Myeloma
5. Fibrous dysplasia
6. Paget’s disease