slide flashcards W2D2

1
Q

what is dale’s law

A

that each neuron specializes and synthesizes only one neuron (WRONG)

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2
Q

what does it mean if a neuron is serotogenic

A

produces serotonin, does NOT mean that it has serotonin receptors or only responds to serotonin

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3
Q

what does it mean if a neuron is dopamegenic

A

produces dopamine, does NOT mean that it has dopamine receptors or only responds to dopamine

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4
Q

true or false: neurotransmitters are taken up by receptors/receiving neuron

A

FALSO

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5
Q

what protiens bring vesicles carying neurotransmitters to cell membrain to be released into synapse

A

snare protiens

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6
Q

what is clathrin and what does it do

A

protien that reuptakes/recycles vesicles (similar to transporter protiens and neurotransmitters)

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7
Q

ligand (def)

A

something that binds to a receptor

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8
Q

exogenous (def)

A

made outside of the body (foreign)

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9
Q

endogenous (def)

A

made inside the body

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10
Q

name the catecholamines

A

dopamine, epinephrine, norepinephrine

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11
Q

name the indoleamine(s)

A

serotonin

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12
Q

name the imidazoleamine(s)

A

histamine

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13
Q

name the amino acid neurotransmitters

A

glutamate, aspartate, GABA, glycine

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14
Q

name the peptide neurotransmitters

A

opiodes, vasopressin, oxytocin

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15
Q

name 3 atypical neurotransmitters

A

anandamide, nitric acid, carbon monoxide

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16
Q

what causes a neuron to release peptides in addition to neurotransmitters

A

HIGH firing rate (this is REALLY important info)

17
Q

name the neuromodulators

A

acetylcholine, dopamine, serotonin

18
Q

process of acetylcholine synthesis + degradation

A

choline + acetylCoA——–ChaT enzyme——–acetylcholine——-AChE enzyme—-choline + acetyleCoA

19
Q

order of catecholamine synthesis

A

tyrosine—–TH enzyme——-L-dopa——enzyme—–dopamine—-enzyme—-norepinephrine——enzyme—–epinephrine

20
Q

what does dopamine ‘deal with’

A

reward, working memory/planning, motor innitiation + termination

21
Q

what does norepinephrine ‘deal with’

A

allertness, mood, sympathetic activation

22
Q

what does epinephrine ‘deal with’

A

mood, agression, obsessive/compulsive behaviors, anxiety, sleep, pain

23
Q

name the 3 dopamine pathways

A

nigrostriatal, mesolimbic, and mesocortical pathways

24
Q

the BLANK (movement) pathway sends dopamine to BLANK and is associated with BLANK disease

A

nigrostriatal pathway sens dopamine to the midbrain and is associated with parkinsons disease

25
the BLANK (drug reward) pathway sends dopamine to BLANK and is associated with BLANK SYMPTOMS of BLANK disease
the mesolimbic pathway sends dopamine to forebrain and is associated with positive symptoms of skitzofrenia
26
the BLANK (executive functioning) pathway sends dopamine to BLANK and is associated with BLANK SYMPTOMS of BLANK disease
the mesocortical pathway sends dopamine to prefrontal cortex and is associated with negative symptoms of skitzophrenia
27
where is the substantia nigra
midbrain, above crus cerebri
28
which dopamine pathway(s) starts at the substantia nigra and where does it go
the nigrostriatal pathway starts at the substantia nigra and sends dopamine to the midbrain
29
which dopamine pathway(s) starts at the ventral tegmental area and where does it go
the mesolimbic and mesocortical pathways start at the ventral tegmental area/midline/midbrain and send dopamine to the forebrain and prefrontal cortex respectivly