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(60 cards)
What is this
Masquerade syndromes
Conditions mimicing uveitis
Serpiginous choroidopathy:
* Idiopathic, HLA-B7, Retinal S antigen
DDX TB/HSV
Birdshot choroidopathy
* Idiopathic, women, HLA-A29 positive
* AAD to retinal S antigen
* Chronic bilateral blurring of vision
Common recurrances
Multiple evanescent white dot syndrome (MEWDS)
* Idiopathic, female, viral prodrome 50%
* Unilateral loss of vision
Transient with good visual outcome
Punctate inner choroidopathy (PIC)
* Idiopathic, women, myopic
* Never has vitritis
* No treatment
Good visual outcome
Busacca and Koppe nodules from anterior uveitis
FFA of a TB granuloma
1/2: Acutre retinal necrosis
3: Progressive outer retinal necrosis
Viral retinitis:
* HSV/HZO/CMV * Acute retinal necrosis (ARN) ○ Triad of: Vitritis, Arteritis, Periphlebitis ○ Confluent peripheral retinal necrosis * Progressive outer retinal necrosis ○ Cracked mud appearance * IV acyclovir 2w + steroids
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)
* Idiopathic, HLA B7/DR2
* Sudden bilateral loss of vision
Can cause disc edema, KP’s, RD, Venous occlusions
CMV retinitis
* AIDS and organ transplant
* Frosted bushfire
IV acyclovir
Papillary OSSN
ICG of MEWDS
Multiple evanescent white dot syndrome (MEWDS)
* Idiopathic, female, viral prodrome 50%
* Unilateral loss of vision
* Transient with good visual outcome
Chronic anterior uveitis:
* Duration > 3 months
* Bilateral
Asymptomatic W/Posterior synechiae
Acute anterior uveitis
* Most common form of uveitis
* Idiopathic
* Unilateral
* Pain, redness, watering, photophibia, blur
* Good prognoisis
Non-infectious causes:
* Immune mediated (Ankylosing spondylitis)
* Juvenile idiopathic arthritis
* SLE
* Sarcoidosis
* Behcet’s disease
* Vogt-Koyanagi - Harada disease
* Fuch’s heterpchromic iridocyclitis
Infective causes:
* Lyme disease
* Syphilis
* TB
* Herpes
* Toxo
Signs:
* Conj. Injection
* Corneal edema
○ KP’s (non-granulomatous)
○ Mutton fat KP’s (granulomatous)
○ Stellate KP’s (Fuch’s uveitis syndrome)
* AC cells/flare, Hypopyon, hyphaema
* Iris nodules (Busacca/Koeppe’s), Atrophy, PAS, Neovasc.
* Lens pigment ring, cataract
* IOP fluctuations
○ Low > CB inflammation
○ High > angle closure
* Vitritis
Complications:
* Corneal edema, band keratopathy
* Iris synechae (Pos/Ant)
* Angle PAS
* Lens cataract
* CB membrane
* Secondary glaucoma
Retinitis, optic neuritis
Toxoplasmosis
* Most common
○ Immunocompetent, pets, tropical countries
* Headlight in a fog
* Risk secondary glaucoma
Pyrimethamine + Sulfadiazine + corticosteroids + folic acid
Toxocariasis
* Injestion of pet roundworm
* Granuloma on fundus with TRD
Systemic steroids
Moorens ulcer
6th 7th decade , common in men
Treatment:
topical steroids, conjunctival resection, systemic
immunosuppressive , topical cyclosporin
Terriens marginal degeneration
FFA of CME
Band keratopathy and lenticular cataracts following anterior uveitis
Grade this
Cells
Grade 0 = <1 cells in the field
Grade 0.5 = 1 to 5 cells in the field
Grade 1+ = 6 to 15 cells
Grade 2+ = 16 to 25 cells
Grade 3+ = 25 to 50 cells
Grade 4+ = > 50 + cells
Flare
Grade 0 = none
Grade 1+ = faint
Grade 2+ = moderate (iris & lens detail clear)
Grade 3+ = marked (iris & lens detail hazy)
Grade 4 = intense (fibrin/plastic aqueous)
Nodular | Leukoplakic OSSC
Corneal Farinata
No treatment needed
Lipid keratopathies
Ca in epithelium
Secondary
occurs after injury or infection
vascularisation (herpes simplex & zoster)
Treatment: Argon laser photocoagulation of
feeder vessels, PKP