Small Mechanism Pointers Flashcards
1
Q
Synthesis of tertiary alcohols
A
Unable to stop ketone intermediate as once the ketone is formed, ketones are more reactive than esters therefore ketone will not stop reacting continuously.
2
Q
Protonation with gringard reagents
A
Protonation step destroys a Grignard reagent so once something is protonated it usually means the number of alkyl groups have been added that are needed and no more Gringnard is needed.
3
Q
Nucleophilic addition of a/B-unsaturated carbonyls
A
Reaction is also named: Micheal Reaction, Conjugate addition, 1,4-addition.
4
Q
If secondary alkyl halide, what determines if it goes via SN1 or SN2
A
You have to look at solvent type!
If solvent contains (-OH) inc WATER then = SN1
If solvent contains (C=O) then = SN2
