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Oncology 15% > Solid Organ Cancer > Flashcards

Solid Organ Cancer Flashcards

(43 cards)

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1
Q

What are the 10 medications used for breast cancer?

HINT: Xeroxing An Imaged Kiss Verifies Needed Picture To Tally Love

A

Xeloda, Afinitor, Ibrance, Kisqali, Verzenio, Nerlynx, Piqray, Tykerb, Talzenna, Lynparza

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2
Q

What are the 10 medications used for lung cancer?

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A

Alecensa, Alunbrig, Lorbrena, Xalcori, Zycadia, Gilotrif, Iressa, Tagrisso, Tarceva, Vizimpro

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3
Q

What are the 6 medications used for melanoma?

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A

Mekinist, Tafinlar, Mektovi, Braftovi, Zelboraf, Cotellic

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4
Q

Which 2 medications are used for basal cell carcinoma?

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A

Erivedge and Odonzo

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5
Q

Which 4 medications are used for thyroid cancer?

HINT: Cancer Causes Lumpy Neck

A

Caprelsa, Cometriq, Lenvima, Nexavar

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6
Q

Which 7 medications are used for renal cancer?

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A

Afinitor, Cabometyx, Inlyta, Lenvima, Nexavar, Sutent, Votrient

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7
Q

Which 4 medications are used for gynecologic cancers?

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A

Rubraca, Zejula, Lynparza, Lenvima (endometrial)

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8
Q

Which 4 medications are used for liver cancer?

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A

Cabometyx, Lenvima, Nexavar, Stivarga

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9
Q

Which 6 medications are used for prostate cancer?

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A

Erleada, Nubeqa, Xtandi, Zytiga, Yonza, Rubraca

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10
Q

Which 2 medications are used for pancreatic cancer?

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A

Lynparza, Tarceva

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11
Q

Which 2 medications are used for CNS cancer?

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A

Gleostine, Temodar

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12
Q

Which 4 medications are used for colorectal cancer?

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A

Stivarga, Lonsurf (trifluridine and tipiracil), Braftovi, Xeloda

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13
Q

Which 3 medications are used for neuroendocrine tumors?

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A

Afinitor, Sutent, Xermelo

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14
Q

Which medications are used for sarcomas?

HINT: Vote stupid sarcasically

A

Votrient-hair color changes

Stivarga and Sutent are for GISTs

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15
Q

What two medications is used for gastrointestinal stromal tumors (GISTs)?

HINT: Supporting Supplies

A

Stivarga, Sutent

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16
Q

Which 3 types of solid organ cancers are treated by Afinitor (everolimus)?

A

breast, renal and neuroendocrine

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17
Q

Which 2 types of solid organ cancers are treated by Cabometyx (cabozatinib)?

A

renal and liver

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18
Q

Which 4 types of solid organ cancers are treated by Lenvima (lenvatinib)?

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A

thyroid, renal, liver and endometrial

19
Q

Which 3 types of solid organ cancers are treated by Lynparza (olaparib)?

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A

breast, gynecologic and pancreatic

20
Q

Which 3 types of solid organ cancers are treated by Nexavar (sorafenib)?

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A

thyroid, renal and liver

21
Q

Which 2 types of solid organ cancers are treated by Rubraca (rucaparib)?

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A

gynecologic and prostate

22
Q

Which 3 types of solid organ cancers are treated by Stivarga (regorafenib)?

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A

liver, colorectal and GIST

23
Q

Which 2 types of solid organ cancers are treated by Tarceva (erlotinib)?

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A

lung and pancreatic

24
Q

Which 2 types of solid organ cancers are treated by Xeloda (capecitabine)?

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A

breast and colorectal

25
Which **6** mechanisms of action are used to treat **breast cancer**?
* pyrimidine antimetabolite * mTOR inhibitor * CDK4/6 inhibitor * Tyrosine Kinase Inhibitor (TKI) * HER1, HER2, HER4 * EGFR * PhosphatidyLinositol-3-Kinase (Pl3K) Inhibitor * Poly (ADP-ribose) polymerase (PARP) enzyme Inhibitor
26
Which types of Tyrosine Kinase Inhibitors are used to treat **lung cancer**?
* anaplastic lymphoma kinase inhibitor * EGFR inhibitor
27
Which two mechanisms of action are used to fight skin cancer?
* Mitogen-activated extracellular kinase (MEK) inhibitors * Protein kinase B-raf (BRAF) inhibitors
28
Which two types of TKIs are used to treat thyroid cancers?
They are all VEGF inhibitors; Caprelsa is also a EGFR inhibitor.
29
Which 2 mechanisms of action are used to treat renal cancer?
* mTOR inhibitor * TKI; VEGF inhibitors (all generic names end in "*nib*")
30
What is the only mechanism of action currently used to treat liver cancer?
All four of the medications currently approved to treat liver cancer are TKIs, (**VEGF inhibitors**).
31
Gynecologic cancers are treated with which type of medication?
Three of the meds approved for gynecologic cancers are PARP inhibitors and one is a TKI (VEGF inhibitor).
32
Which 3 types of drugs are currently used to treat prostate cancer?
* Androgen Receptor Inhibitor (3) * CYP17 inhibitors (2) * PARP inhibitor (1)
33
Which 2 types of drugs are used to treat pancreatic cancer?
* PARP inhibitor * TKI (EGFR inhibitor)
34
Alkylating agents are used to treat which type of solid organ cancers?
CNS cancers
35
5 different mechanisms of action are currently used to treat colorectal cancers. What are they?
* TKI (VEGF inhibitor) * Thymidine-based nucleic acid * Phosphorylase inhibitor * BRAF inhibitor * Pyrimidine antimetabolite
36
Each of the 3 drugs currently used to treat neuroendocrine tumors has a different mechanism of action. What are they?
* mTOR inhibitor * TKI (VEGF inhibitor) * Tryptophan hydrolase inhibitor
37
All sarcomas (soft tissue and GISTs) are currently treated by which type of medication?
TKI (VEGF inhibitors) are currently the only MOA approved to treat either soft tissue sarcomas or GISTs. There are 3. * Votrient for STS * Stivarga and Sutent for GISTs
38
Which 2 types of solid organ cancers are treated with **Braftovi**?
Melanoma and colorectal cancer
39
Which 2 types of solid organ cancers are treated with **Votrient**?
renal and soft tissue sarcoma
40
Which of the drugs used to treat breast cancer do not interact with grapefruit?
Xeloda, Piqray, Talzenna and Lynparza
41
Which of the drugs used to treat breast cancer are co-administered with Xeloda?
* Nerlynx for advanced or metastatic HER2+ * Xeloda 750mg/m2 BID on days 1-14 of 21 * Tykerb for advanced or metastatic HER2+ * Xeloda 1000mg/m2 BID on days 1-14 of 21
42
PPIs should be avoided with which medications used to treat solid organ cancers?
* Tagrisso * Vizimpro * Votrient * Nerlyx, separate from antacids by 3 hours
43
Which of the drugs for solid organ cancers should be taken with food?
* Xeloda * Ibrance **capsules** * Nerlynx * Piqray * Alecensa * Zycadia * Nubeqa * Lonsurf

Oncology 15% (3 decks)

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