somatosensory II Flashcards

(44 cards)

1
Q

fast pain receptor

A

mechanical and thermal nocioceptors

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2
Q

fast pain fiber type

A

small myelinated

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3
Q

fast pain tracts

A

neospinothalamic

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4
Q

fast pain thalamus

A

lateral VPL

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5
Q

fast pain function

A

sharp localized pain

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6
Q

slow pain receptor

A

polymodal nocioceptors

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7
Q

slow pain fiber type

A

unmyelinated

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8
Q

slow pain tracts

A

paleospinothalamic

spinoreticulothalamic

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9
Q

slow pain thalamus

A

medial thalamus

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10
Q

slow pain cortex

A

frontal and limbic

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11
Q

slow pain function

A

cortical arousal, affect

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12
Q

nociception proteases

A

breakdown kininogen to bradykinin

bradykinin bind to receptors that activate ion channels

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13
Q

heat over ___ opens heat sensitive ion channels on nociceptors

A

43

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14
Q

oxygen deprivation-

anaerobic metabolism release

A

lactic acid

–> high levels of H

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15
Q

polymodal

A

mechanical, thermal, chemical stimuli

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16
Q

capsaicin activates

A

TRPV1 receptor

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17
Q

trpv1 channels open at

A

lower temps

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18
Q

aspirin inhibits enzymes for ____ synthesis

A

prostaglandin

19
Q

what fibers for pain and temp, some touch

A

A-delta(III)

small, thinly myelinated

20
Q

what fibers for slow pain and temp

21
Q

ascending pathways important for

A

position of body in space

arousal

22
Q

anterolateral system or spinothalamic pathway

A

pain temp itch touch

23
Q

pain fibers enter dorsal root enter zone ___

24
Q

dorsal root entry zone also known as

A

zone of lissauer

25
second order neurons ascend contralaterally in the
medulla pons midbrain
26
second order neurons synapse in
thalamus
27
neospinothalamics synapse in
VP nucleus
28
spinoreticular tract is information
to the reticular nuclei which project to intralaminar nuclei of thalamus important in arousal
29
spinomesencephalic tract information to
midbrain tectum -coordinates eye and head movements periaqueductal gray matter -pain regulation
30
dorsal column medial lemniscus for
vibration, proprioception, fine touch
31
anteral lateral pathways for
pain, temp, crude touch
32
in spinal cord ALS and DC-ML pathways on what sides
opposite
33
ALS and DCML pathways come together in
caudal medulla
34
with hemisection of spinal cord patient loses
pain from opposite side of body about 2 levels below lesion | touch etc on same side
35
spinomesencephalic tract projects to
superior colliculus orienting to pain stimulus | periaqueductal gray-pain modulation
36
thalamus projects to
primary somatic sensory cortex
37
posterior thalamic nuclei input projects to
ALS | insular cortex
38
medial dorsal nucleus input projection
ALS | anterior cingulate cortex and orbitofrontal
39
thalamus plays role in
affecttive and motivational aspects of pain and in memory fo painful stimuli
40
cortex for painful stimuli
insular cortex and anterior cingulate
41
cortical projections from layers 5/6 project to | and modulate...
thalamus brainstem spinal cord modulate sensory info thats ascending
42
pain modulation from___ to ___
periaqueductal gray | nucleus raphe magnus
43
neurons in raphe magnus project to | excite..
spinal cord excite interneurons -enkephalinergic -inhibits 1st and 2nd order pain neurons
44
neurons in locus cereleus are
noradrenergic