somnul 2 Flashcards

1
Q

what do we mean by enough sleep

A

there are individual differences when it comes to sleep requirements

newborn babies need 14-17h sleep

recommended amount of sleep decreases through the life course

adults: 7-9h

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2
Q

what are the individual differences

A

some people can function on less sleep than hours

when people sleep very long or very short, could be a sign of health problems

you may be sleep deprived, if you can’t wake up when alarm goes off, and know that you are not functioning to the best of your ability

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3
Q

major effects of total sleep deprivation

A

scientists looked at effects of total sleep deprivation in rats
rats were put on a rotating disk
if they stopped moving, they would be pushed and thrown in to water

there was wight loss
skin became problematic
problems with regulating temperature
in 2-3w they died

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4
Q

fatal familial insomnia FFI

A

a rare genetic disease

ppl miss out on sleep and die within an average of 18m

abnormal proteins build up in the brain

attacks the thalamus which is important in sleep-wale cycles

results in reduction in sleep length and deterioration of sleep stages

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5
Q

does the sleeplessness lead to death in FFI

A

symptoms of FFI include dementia, problems speaking and swallowing

it’s not insomnia that is leading to death - not clear

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6
Q

sleep deprivation in humans

A

1964

17yo agreed to stay awake for 11 days
beat the world record

no caffeine available

he showed marked circadian rhythms in sleepiness

occasional hallucinations

showed ataxia (inability to perform coordinated movements)

increased irritability

speech difficulties

deficits in attention and memory

reduction in body temperature

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7
Q

can you catch up on missed sleep

A

Randy was allowed to sleep again

on first night he slept for 15 hours

by the end of the week he was getting 9 hours

a week after experiment he was getting 7h

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8
Q

what happened when randy fell asleep after the experiment

A

his body prioritised REM sleep and deep NREM sleep

there was less light sleep

so this tells us these types of sleep are important

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9
Q

effect of sleeplessness in crashes

A

multiple crashes due to sleep deprivation

more than 20% of fatal crashes involve a driver who was drowsy

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10
Q

sleep deprivation impairing performance

A

ppts sleep deprived for 28 hours

another group was given alcohol steadily

hand-eye coordination was assessed repeatedly

RESULTS
decrease in performance as a result of being awake for 24 hours was equivalent to having a blood alcohol concentration above the drink drive limit

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11
Q

the way we sleep is linked to health

A

the way u sleep is linked to
ADHD
ASD
anxiety
depression
PTSD
conduct disorder

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12
Q

effect on short sleep on immune system

A

short sleep compromises the immune system

sleep assessed for a week in ppts

ppts were given nasal drops - virus that causes common cold

those who got up to 6h sleep were more likely to get a cold than those who slept for longer periods

BUT
when sleep length was reported by self report, these associations weren’t found - results from studies may depend on whether we use objective or subjective measures

possibility: ppl aren’t good at estimating their own sleep length

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13
Q

cost of not getting enough sleep

A

cost of insufficient sleep on the economy

decrease in potential in adolescence
decrease in performance
absenteeism

insufficient sleep costs the UK £40 billion each year

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14
Q

theories of sleep

A

evolutionary theory
restorative theory
information/memory processing
theories of dreaming

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15
Q

evolutionary theory

A

during sleep we become less aroused

we become vulnerable to predators

lack movement - cannot escape quickly

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16
Q

sleep as a way to conserve energy

A

sleep might have evolved to conserve energy

sleep conserves energy during times of inefficiency

body temp decreases during sleep

muscular tension, blood pressure and rate of respiration is reduced

when we are REM sleep deprived there may be excessive heat loss

when we are NREM deprived we need to use excessive energy in oder to maintain temperature

17
Q

what are some exceptions

A

REM sleep doesn’t save any energy compared to being awake

dolphins
- one hemisphere goes into deep sleep
- the other stays awake
- they can keep swimming so they are not conserving much energy

18
Q

update of evolution of sleep

A

different behavioural states allow for energy to be allocated optimally to vital biological processes

when awake we can use energy for reproduction

when we sleep we use energy for neural network reorganisation and growth

19
Q

restorative theory

A

when we are asleep we restore our brain and body

when we sleep our metabolic requirements are replenished

growth hormone is released to the greatest extent during our deep sleep - allows for cell reproduction

sleep allows us to restore hormone and neurotransmitter levels

sleep allows growth of synaptic connections

20
Q

against restorative thoery

A

protein synthesis occurs 24h a day, not just during N3 altough it seems to peak in N3

amount of sleep does not appear to decrease when our level of daytime activity decreases

theory predicts that more active species will sleep longer. however, 1 of the least active creatures, the sloth, sleeps for about 20h per day

21
Q

metabolic homeostasis

A

metabolic - the chemical reactions in our cells

homeostasis - balance, maintaining equilibrium

22
Q

the role of sleep in clearing metabolites from brain

A

sleep in mice
during sleep, there was a 60% increase in interstitial space, resulting in an increase in the exchange of cerebrospinal fluid with interstitial fluid

this allowed the clearance of beta amyloid from the brain

toxins build up in the brain when we are awake - beta amyloid - an amino acid centrally involved in Alzheimer’s

when we sleep certain brain cells (glial cells) shrink and this allows more space for fluid to remove toxins from brain

23
Q
A

scientists who imaged the brain of mice, showed that the glymphatic system became 10x more active when them mice were asleep

24
Q

sleep in supporting immune system

A

defence against pathogens is mediated by central nervous system and changes to concentrations of immune signalling molecules called cytokines

concentrations of cytokines naturally vary with sleep wake cycles

cytokines can cause immune system to increase t cells to help fight infections

25
Q

information and memory processing theory

A

sleep may have evolved for learning and memory consolidation

the ability to learn and memorise info is metabolically expensive

during sleep, the info coming through sensory systems is minimal - metabolic demands associated with this are low

-during this inactive phase, new brain circuits are laid down

26
Q

how is memory consolidated during the mind

A

during sleep, newly formed memory representations are reactivated

this reactivation aids in the redistribution of memories from STM in a part of the brain called the hippocampus into LTM in areas of the cortex

this reactivation process occurs during NREM sleep

REM sleep is thought to stabilise reactivated memories to ensure they remain in LTM, integrated with other relevant memories

27
Q

studies supporting info memory theory

A

young adults reporting poor sleep quality also performed less well on attention tasks

ppts 16-19 who get less sleep and whose schedules differs most at the weekend compared to the week get a lower grade point average

difference in terms of schedule from weekdays to weekends is called a social jet lag - operating on a different schedule on our days off

28
Q

sleep important for insight

A

mendeleyev

he was struggling with some of the rules in order to develop the table and the key rule came to him in a dream

29
Q

support for sleep resulting in insight

A

3 groups
each had 3 training blocks and 10 final blocks

the difference was the period in between their training and final block

they were either asleep from 11pm-7am

awake from 11pm-7am

or awake in the day from 11am-7pm

in the training block ppts had to analyse and 8 digit string of 1s, 4s and 9s from left to right

task was to work out the rules: can u see what the rules are

if digits are the same, the response should be the same digit

if digits were different the response should be the remaining digit

RESULTS
20% of those who were awake during the day and awake during night got answer correct
60% got correct response when sleeping

30
Q

can brain respond to stimuli when asleep

A

our brain can respond to auditory stimuli when we are asleep

k complexes are present during N2 sleep

ppts asked to remember target names whilst they were awake

then when they were asleep names were played to them, including their own name and other controls

k complexes appeared in N2 when names were played

k complexes responses to target names were larger and more reliable than control names

largest k complexes to their own name

31
Q

can we learn when we are asleep

A

new born babies were played tunes

when tunes were played, experimenter gave air puff to baby - air blown gently into their eyes

upon hearing the tune they learnt to scrunch up their eyes

unlikely more complex infor can be learnt this way

attempts to learn new info while asleep - focusing on other age groups have failed

32
Q

theories of dreaming

A

altered state of consciousness

subjective cognitive experience

wake somebody up and ask what they have been dreaming

so dreams are difficult to study

most occur during REM, but also possible to dream during NREM

33
Q

theories of dreaming

A

focus on dream imagery and its meaning

Freud

dreams are a road to unconscious activities of the mind

certain desires have been repressed in the unconscious mind and are too distressing for the conscious mind to be aware of these

dream analysis identifies hidden symbols

34
Q

problem solving theories of dreams

A

dream imagery reflect current events in one’s life

brain attempts to solve problems in one’s life and come with solutions and help us come with major life stresses

adaptive response to stressful situations

35
Q

activation synthesis theory of sleep

A

during rem sleep brain stem areas and reticular formation are highly active

this leads to cortical arousal including the arousal of specialised areas for visual, motor and auditory processing

we then try to make sense of this which can result in dreaming