Sos- Cerebral Neoplasias Flashcards
(84 cards)
1
Q
tumor location
A
meningioma
2
Q
tumor location
A
astrocytomas
oligodendroglioma
ganglioglioma
3
Q
metastatic tumor location
A
anywhere
4
Q
tumor location
crosses corpus callosum
A
glioblastoma
lymphoma
5
Q
tumor location
A
ependymoma
central neurocytoma
colloid cyst
6
Q
tumor location
A
pituitary adenoma
craniopharyngioma
7
Q
tumor location
A
medulloblastoma
ependymoma
pilocytic astrocytoma
hemangioblastoma
8
Q
A
metastatic neoplasms
9
Q
what kind of metastatic neoplasm
A
melanoma
10
Q
metastatic hemorrhagic neoplasms
A
lung
kidney
melanoma
choriocarcinoma
11
Q
location?
A
gray-white matter junction
12
Q
2 types of infiltrating gliomas
A
astrocytoma
oligodendroglioma
13
Q
non-infiltrating glioma
A
gangliomas
14
Q
chaotic gray matter
A
metastatic neoplasm
15
Q
A
metastatic neoplasm
16
Q
HMG-45
A
melanoma stain
17
Q
A
metastatic neoplasm
18
Q
A
metastatic brain cancer
19
Q
A
metastatic brain cancer
20
Q
astrocytoma
oligodendroglioma
A
infiltrative lesions
21
Q
Arise from neoplastic astrocytes and oligodendrocytes within the white matter and infiltrate into gray matter
A
infiltrative gliomas
22
Q
In children, where are the most common locations of infiltrative gliomas
A
brain stem or thalamus
23
Q
stain for astrocytomas
A
GFAP+
24
Q
infiltrating gliomas
A
astrocytomas
oligodendrogliomas
25
GFAP+
astrocytes
26
what glial cell attaches to neurons and blood vessels
astrocytes
27
normal or glioma
normal
28
GFAP+
astrocytoma
29
normal or glioma
glioma
30
WHO grade II
pleomorphic astrocytes
Astrocytoma
31
WHO grade III
pleomorphic astrocytes
mitoses (just 1)
anaplastic astrocytoma
32
WHO grade IV
pleomorphic astrocytes
mitoses
necrosis and/or microvascular proliferation
glioblastoma multiforme (GBM)
33
in white matter of young adults (30-40 yrs)
>10 yrs of survival
astrocytoma WHO grade II
34
infiltrating pleomorphic cells with increased cellularity
diffuse astrocytoma WHO grade II
35
normal or neoplastic
normal
36
neoplastic or normal
pale=edema
grade II astrocytoma
37
adult 50 yrs
2-4 yr survival
who grade III
anaplastic astrocytoma
38
1 mitotic feature
grade III what
anaplastic astrocytoma
39
normal or neoplastic
neoplastic grade III
40
50-60 yrs
irregular ring enhancing
1 yr survival
WHO grade IV
glioblastoma multiforme
41
"butterfly lesion"
glioblastoma multiforme
WHO grade IV
42
mitotic activity,
endothelial vascular proliferation
and necrosis
glioblastoma multiforme
43
mitotic activity,
endothelial vascular proliferation
and necrosis
glioblastoma multiforme
44
pseudopalasading necrosis (neoplastic cells around vessel)
glioblastoma multiforme
45
necrosis w/ neoplastic cells around
KNOW THIS
glioblastoma multiforme (GBM)
46
women>men
characteristic loss of chromosomes 1p, 19q
oligodendroglioma
47
oligodendroglioma has characteristic loss of chromosomes ______
1p, 19q
48
"fried egg" appearance
oligodendroglioma
49
Perinuclear halos or fried egg appearance
Delicate capillaries
Calcification
oligodendroglioma
50
infiltrates the corpus callosum
B-cell type
lymphoma
51
explosion of lymphocytes
lymphoma
52
lymphoma
53
out of the two neoplasms that cross corpus callosum, which one has best prognosis
lymphoma
53
3 periventricular neoplasms
ependymomas
central neurocytomas
colloid cyst
53
pt comes in with vision problems
(ACTH, GH, or prolactin producing)
anterior pituitary adenomas
54
pituitary adenoma (GH producing)
55
pituitary adenoma (ACTH producing)
56
oligomenorrhea
amenorrhea
galactorrhea
pituitary adenoma (prolactinoma)
57
normal pituitary gland
58
more acidophils
GH adenoma
59
more basophils
ACTH adenoma
60
hemorrhage in pituitary adenoma
pituitary apoplexy
61
Rare benign tumors derived from embryonic pituitary tissue
(HAs, vomiting, vision loss, polyuria)
Craniopharyngioma
62
calcification
Craniopharyngioma
63
calcification
Craniopharyngioma
64
Leftover from developing pituitary area: Rathkes pouch (in b/t anterior and posterior pituitary)
Rathke's cleft cyst
65
Mom presents to your pediatric clinic with her 5-year-old child and a chief complaint of her child awakes from sleep with a headache that improves during the day, and vomiting
choroid plexus papilloma
(see hydrocephalus and enlarged ventricles)
66
rare benign _______tumor
choroid plexus
67
papillary structures in CSF, what to think
choroid plexus
68
You examine the brain of a 20-year-old man who was in a MVA
He had a recent history of fainting with a quick recovery
colloid cyst in foramen of monro
69
colloid cyst
what kills the pt
blood from MVA into ventricular space
70
Rare benign epidermal cyst arising from the third ventricle near the interventricular foramen
Can cause acute obstruction of CSF flow “drop attacks’ can be fatal
colloid cyst
71
"drop attacks"
colloid cyst
72
children
astrocytes
rare
pilocytic astrocytoma of optic n.
73
pilocytic astrocytoma of optic nerve is associated w/ what
neurofibromatosis type I
74
child
4th ventricle
ventricle enlargement
crying, wide gait
pilocytic astrocytoma
75
dilated astrocystic processes
Rosenthal fibers
76
most common low grade/benign glial tumor in children (see Rosenthal fibers)
Pilocytic Astrocytoma
77
most common high grade/malignant pediatric CNS neoplasm
medulloblastoma
78
(3rd ventricle huge and dark and dilated)
child
medulloblastoma
79
homer-wright rosettes
neuroblastoma in the brain
medulloblastoma
80
homer wright rosettes
synaptophysin +, chromogranin +
medulloblastoma
81
found only in ventricles
synaptophysin and chromogranin +
(similar to oligo, but this one is a neuron) "fried egg"
central neurocytoma
82
difference b/t oligodendroglioma and central neurocytoma
neurocytoma found in ventricles
oligodendroglioma found in neocortex
neurocytoma made from neurons
oligodendroglioma form oligodendocytes
