Sources Of Drugs (chap 1) Flashcards
(55 cards)
What is pharmacy
Pharmacy talks only about the drug or it is the profession or science of preparing, dispensing and ensuring the safe and effective use of the drug
What is pharmacology
Pharmacology is the study of how the drug interacts on the living organism, it focuses on the
1. Mechanisms of the drug action
2. Effects of the drug on the system
3. Toxicity and its side effects
What is drug
Any substance or product that is intended to used to
1. Prevent, treat and diagnose a disease
2. Alternatively biological processes or
3. Modify physiological functions
For the benefit of the patient
What is pharmacognosy
The study of medicine or drug that is produced from natural sources such as plants, animals and microbes
Drug(example) that is used to
1.prevent
2.treat
3.diagnose
4. Modify physiological processes
- Vaccines
- Paracetamol
- Iohexol for CT scans
- Supplements for vitamin
What are the two main points to look in a drug
Safety and efficacy(meaning effectiveness)
What is clinical and pre clinical
Pre clinical are the trails performed on (mainly) animals before it is used on humans while clinical is the trail performed on humans
Name the source of drugs
- Plant sources
- Animal sources
- Microbiological sources
- Mineral sources
- Synthetic and semi synthetic sources
- Recombinant dna technology
- Monoclonal antibodies
( 1. To 4. Main points)
Name some plant drugs sources
- Nicotiana tobacum
- Opium or poppy seeds
- Atropa belladonna
4.Foxglove or digitalis purpurea - Vinca rosea
- Cinchona pubescens
- Rauwolfia serpentina
(Main example 1 to 5)
Nicotiana tobacum produces which drug and what is it used for
Drug: nicotine
Use: stimulate the nicotine receptors
(Causes rapid neural and neuromuscular transmission)
What drug opium seed produces and uses
Drug : morphine
Uses: analgesic ( painkillers)
(Helps to treat pain and used as sedative)
Sedative helps in slowing down brain functioning
Atropa belladonna produces which drug and uses
Drug: atropine
Uses: anticholinergic drug for op poisoning (organophosphate poisoning) also used primarily to dilute the eyes
[Anticholinergic drugs block the activity of acetylcholine, a neurotransmitter that controls involuntary muscle movements]
What does belladonna mean and what is the history related to that
Belladonna means pretty woman as women used the juice of the berries of this plant to dilute their eyes since it was considered pretty at that time period
Vina rosea produces which drug and uses
Drug: Vinca alkaloid ( starts with ‘vin’)
Uses: anticancer, diabetes and high blood pressure
Foxglove or digitalis purpurea produces which drug and uses
Drug: digitalis
Uses: to treat heart failures (CHF) and heart rhythm problems
Which famous artist is associated with digitalis and what r the side effect
Artist: Vincent Van Gogh
Side Effects: yellowish vision and hallucinations
Cinchona pubescens produce which drug and uses
Drug: Quinine
Uses: malaria
Rauwolfia serpentina produces which drug and uses
Drug: rauwolfia alkaloid example reserpine
Used : to treat hypertension ( anti hypertensive agent)
Rauwolfia is commonly found in
India
- Which plant is the source of codeine, a cough suppressant?
A) Opium poppy plant (Papaver somniferum)
B) Willow bark (Salix alba)
C) Jaborandi plant (Pilocarpus jaborandi)
D) Foxglove plant (Digitalis purpurea) - What is the primary use of aspirin derived from willow bark?
A) Treating muscle spasms
B) Relieving pain and reducing inflammation
C) Dilating pupils
D) Lowering blood pressure - Which plant is used to treat glaucoma?
A) Opium poppy plant (Papaver somniferum)
B) Jaborandi plant (Pilocarpus jaborandi)
C) Deadly nightshade plant (Atropa belladonna)
D) Indian snakeroot plant (Rauwolfia serpentina) - What is the effect of atropine derived from the deadly nightshade plant?
A) Constricts pupils
B) Dilates pupils
C) Lowers blood pressure
D) Relieves pain - Which compound is used to treat congestive heart failure?
A) Digoxin
B) Caffeine
C) Hyoscyamine
D) Reserpine - What is the primary use of caffeine derived from the tea plant?
A) Treating muscle spasms
B) Relieving pain and reducing inflammation
C) Stimulating the central nervous system
D) Lowering blood pressure - Which plant is the source of benzoin, an oral disinfectant?
A) Styrax tonkinensis
B) Opium poppy plant (Papaver somniferum)
C) Willow bark (Salix alba)
D) Jaborandi plant (Pilocarpus jaborandi)
Here are the answers:
- A) Opium poppy plant (Papaver somniferum)
- B) Relieving pain and reducing inflammation
- B) Jaborandi plant (Pilocarpus jaborandi)
- B) Dilates pupils
- A) Digoxin
- C) Stimulating the central nervous system
- A) Styrax tonkinensis
Here are 7 MCQs based on the list:
- Which hormone is responsible for preparing the body for “fight or flight” responses?
A) Thyroxine
B) Oxytocin
C) Adrenaline (Epinephrine)
D) Insulin - Which digestive enzyme breaks down proteins into smaller peptides and amino acids during digestion?
A) Pepsin
B) Trypsin
C) Pancreatin
D) Both A and B - What is the primary use of insulin?
A) Treating diabetes
B) Preventing thrombosis
C) Regulating metabolism
D) Stimulating uterine contractions - Which substance is used as an antidote for heparin?
A) Protamine Sulphate
B) Antitoxin (H66)
C) Fibrinolysin
D) Cod Liver Oil - What is the primary function of oxytocin?
A) Regulating metabolism
B) Stimulating uterine contractions
C) Breaking down blood clots
D) Immunizing against diseases - Which substance is derived from cod liver and is used to treat vitamin deficiencies?
A) Cod Liver Oil
B) Antitoxin (H66)
C) Fibrinolysin
D) Pancreatin - What is the medical condition characterized by the formation of blood clots within blood vessels?
A) Thrombosis
B) Diabetes
C) Metabolism disorder
D) Digestive enzyme deficiency
Here are the answers:
- C) Adrenaline (Epinephrine)
- D) Both A and B
- A) Treating diabetes
- A) Protamine Sulphate
- B) Stimulating uterine contractions
- A) Cod Liver Oil
- A) Thrombosis
List the animal sources
-
Adrenaline (Adr.) - Epinephrine
- Source: Adrenal glands
- Function: Prepares the body for “fight or flight” responses
-
Thyroxine
- Source: Sheep thyroid gland
- Function: Regulates metabolism, growth, and development
-
Oxytocin
- Source: Posterior pituitary gland
- Function: Stimulates uterine contractions during childbirth and milk letdown during lactation
-
Pepsin, Trypsin
- Source: Stomach lining
- Function: Break down proteins into smaller peptides and amino acids during digestion
-
Pancreatin
- Source: Pancreas (pig)
- Function: Breaks down carbohydrates, fats, and proteins
-
Pepsin
- Source: Cow stomach
- Function: Digestive enzyme
-
Insulin
- Source: Cow/Pig Pancreas
- Use: Diabetes
-
Protamine Sulphate
- Source: Fish Sperm
- Use: Antidote for heparin
-
Heparin
- Source: Ox Lung
- Use: Anticoagulant
-
Cod Liver Oil
- Source: Cod Liver
- Use: Vitamin A & D deficiencies
-
Antitoxin (H66)
- Source: Horse serum
- Use: Treats diseases such as diphtheria and tetanus
-
Vaccine
- Source: Blood serum
- Function: Immunization against specific diseases
-
Fibrinolysin
- Source: Human plasma
- Function: Breaks down blood clots (fibrin) to prevent thrombosis
-
Thrombosis
- Condition: Formation of blood clots within blood vessels, leading to blockages and tissue damage.
Here are 7 more MCQs:
- Which part of the body produces adrenaline (epinephrine)?
A) Thyroid gland
B) Adrenal glands
C) Pancreas
D) Pituitary gland - What is the primary function of pancreatin?
A) Breaking down proteins
B) Regulating metabolism
C) Breaking down carbohydrates, fats, and proteins
D) Stimulating uterine contractions - Which substance is used to treat diseases such as diphtheria and tetanus?
A) Antitoxin (H66)
B) Fibrinolysin
C) Cod Liver Oil
D) Protamine Sulphate - What is the primary use of heparin?
A) Treating diabetes
B) Preventing thrombosis
C) Regulating metabolism
D) Stimulating uterine contractions - Which part of the body produces thyroxine?
A) Thyroid gland
B) Adrenal glands
C) Pancreas
D) Pituitary gland - What is the primary function of fibrinolysin?
A) Breaking down blood clots
B) Regulating metabolism
C) Breaking down carbohydrates, fats, and proteins
D) Stimulating uterine contractions - Which substance is derived from fish sperm and is used as an antidote for heparin?
A) Protamine Sulphate
B) Antitoxin (H66)
C) Fibrinolysin
D) Cod Liver Oil
Here are the answers:
- B) Adrenal glands
- C) Breaking down carbohydrates, fats, and proteins
- A) Antitoxin (H66)
- B) Preventing thrombosis
- A) Thyroid gland
- A) Breaking down blood clots
- A) Protamine Sulphate
Here are 7 fill-in-the-blank questions:
- The hormone _______________________ is produced by the adrenal glands and prepares the body for “fight or flight” responses.
- The digestive enzyme _______________________ breaks down proteins into smaller peptides and amino acids during digestion.
- The medicinal substance _______________________ is used to treat diabetes and is produced by the pancreas of cows and pigs.
- The anticoagulant _______________________ is produced by ox lungs and prevents the formation of blood clots.
- The substance _______________________ is used as an antidote for heparin and is produced by fish sperm.
- The medical condition _______________________ is characterized by the formation of blood clots within blood vessels, leading to blockages and tissue damage.
- The substance _______________________ is used to immunize against specific diseases and is produced from blood serum.
Here are the answers:
- Adrenaline (Epinephrine)
- Pepsin, Trypsin
- Insulin
- Heparin
- Protamine Sulphate
- Thrombosis
- Vaccine