Specific Antidotes Flashcards Preview

Step 1 Pharmacology > Specific Antidotes > Flashcards

Flashcards in Specific Antidotes Deck (25):
1

Acetaminophen toxicity

Replenishes glutathione
N-acetylcysteine

2

ACh Esterase inhibitors
Organophosphates

Atropine
Pralidoxime

where Atropine>Pralidoxime

3

Amphetamine overdose

NH4Cl to acidify the urine becase amphetamines are basic

4

Heparin

Protamine sulfate

5

Iron overload

De - feroxamine
De - ferasirox

6

Opiods

Naloxone
Naltrexone

7

Warfarin

Vitamin K (delayed effect)
Fresh frozen plasma (more immediate effect)

8

Beta blocker overdose

Glucagon

9

Antimuscarinic or Anticholinergic agents

Physostigmine salicylate
Control hyperthermia

10

Carbon monoxide poisoning

100% O2
Hyperbaric O2

11

Copper
Arsenic
Gold

Penicillamine

12

Benzodiazepines

Flumazenil

13

Cyanide

Nitrite + thiosulfate
Hydroxocobalamin

14

tPA
Streptokinase
urokinase

Aminocaproic acid

15

Arsenic

Penicillamine

16

TCAs
Tricyclic Acid

NaHCO3 to alkalinize the plasma

17

Copper

Penicillamine

18

Lead poisoning

EDTA
Dimercaprol
Succimer
Penicillamine

19

Salicylates

NaHCO3 to alkalinize the urine
Dialysis

20

Gold

Penicillamine

21

Mercury

DiMERCaprol (BAL)
Succimer

22

Mercury
Arsenic
Gold

DiMERCaprol (BAL)
Succimer

23

Methanol
Ethylene glycol (antifreeze)

Fomepizole is the usual answer
ETOH also works
dialysis works too!

24

METHemoglobin

Methylene blue and Vitamin C

25

Digitalis (Digoxin)

Anti-Dig Fab fragments