Specific protein names

Question 1

dynamin

Answer 1

GTPase that pinches off clathrin coated vesicles

Question 2

proteases, nucleases, glycosidases, aryly sulfatases, lipases, phospholipases, phosphatases

Answer 2

hydrolytic enzymes in lysosomes

Question 3

catalase

Answer 3

enzyme in peroxisomes, breaks down hydrogen peroxide

Question 4

cardiolipin

Answer 4

phospholipid making up the inner mitochondrial membrane

Question 5

cytokeratins

Answer 5

polypeptide of IF class I, all epithelial cells

Question 6

vimentin

Answer 6

polypeptide of IF class II, mesenchymal cells

Question 7

desmin

Answer 7

polypeptide of IF class II, muscle

Question 8

occluden and claudin

Answer 8

zonula occludens / tight junction proteins

Question 9

cadherin

Answer 9

protein of adheren junctions

Question 10

catenin and vinculin

Answer 10

proteins of zonula adherens

Question 11

desmoglein/desmoplakin/pakoglobin

Answer 11

proteins of desmosomes

Question 12

connexon

Answer 12

ordered array of 6 connexin subunits, makes up gap junctions

Question 13

Laminin/collagen/entactin/perlecan

Answer 13

components of basal lamina

Question 14

vincristine

Answer 14

anti-cancer drug : disrupts mitotic spindle: destabilizes

Question 15

colchicine

Answer 15

anti-cancer drug : disrupts mitotic spindle: destabilizes

Question 16

taxol

Answer 16

anti-cancer drug : disrupts mitotic spindle: stabilizes

Question 17

5-fluorouracil

Answer 17

anti-cancer drug : inhibits DNA synthesis: block formation of deoxynuc

Question 18

methotrexate

Answer 18

anti-cancer drug : inhibits DNA synthesis: block formation of deoxynuc

Question 19

cytosine arabinoside

Answer 19

anti-cancer drug : inhibits DNA synthesis: blocks DNA chain elongation

Question 20

caspase

Answer 20

major effector of apoptosis (perhaps role in necrosis?)

Question 21

degenerin

Answer 21

proteins if mutated will trigger necrosis

Question 22

caplain

Answer 22

trigger for necrosis