Spectrum of Activity

Question 1

Aminoglycosides (alone) cover what bacteria?

Answer 1

Gram negative rods and P. aeruginosa

Question 2

Aminoglycosides + cell wall synthesis inhibitor cover what bacteria?

Answer 2

MSSA, MRSA (if the cell wall synthesis inhibitor is active against MRSA), Streptococci, Enterococci, Gram negative rods, and P. aeruginosa

Question 3

Erythromycin covers what bacteria?

Answer 3

Streptococci, most gram negative rods and M. catarrhalis

Question 4

Clarithromycin covers what bacteria?

Answer 4

Streptococci, most gram negative rods including M. catarrhalis and H. influenzae, and atypicals

Question 5

Azithromycin covers what bacteria?

Answer 5

Streptococci, most gram negative rods including M. catarrhalis and H. influenzae, and atypicals

Question 6

Telithromycin covers what bacteria?

Answer 6

Streptococci, most gram negative rods including M. catarrhalis and H. influenzae, and atypicals

Question 7

Lincosamides cover what bacteria?

Answer 7

MSSA, Some community acquired MRSA, streptococci

Question 8

Streptogramins cover what bacteria?

Answer 8

MSSA, MRSA, Streptococci, and E. faecium

Question 9

Oxazolidones cover what bacteria?

Answer 9

MSSA, MRSA, Streptococci, E. faecalis, and E. faecium

Question 10

Chloramphenicol covers what bacteria?

Answer 10

MSSA, Streptococci, E. faecalis, and E. faecium, gram negative rods, bacteroides, and atypicals

Question 11

Tetracyclines cover what bacteria?

Answer 11

MSSA, MRSA (only some strains of community-acquired MRSA), streptococci, some gram negative rods, and atypicals

Question 12

Tigecyclines cover what bacteria?

Answer 12

MSSA, MRSA, Streptococci, vancomycin sensitive E. faecalis, gram negative rods (NOT Proteus spp.), Bacteroides, and atypicals

Question 13

2nd gen fluoroquinolones cover what bacteria?

Answer 13

Gram negative rods, P. aeruginosa, and atypicals

Question 14

3rd gen fluoroquinolones cover what bacteria?

Answer 14

Streptococci, gram negative rods, P. aeruginosa, and atypicals

Question 15

Advanced-gen fluoroquinolones cover what bacteria?

Answer 15

Streptococci, gram negative rods, and atypicals. Bacteroides are covered by moxifloxacin only

Question 16

Metronidazole covers what bacteria?

Answer 16

Bacteroides

Question 17

TMP-SMX covers what bacteria?

Answer 17

MSSA, MRSA (community-acquired only), Streptococci (not S. pyogenes), and gram negative rods

Question 18

Rifampin covers what bacteria?

Answer 18

MSSA, MRSA, and Streptococci, active against any gram + bacteria when used with other antibacterials with gram + activity, especially Staphylococcus spp., Mycobacterium tuberculosis

Question 19

Nitrofurantoin covers what bacteria?

Answer 19

MSSA, Streptococci, Enterococci, and Gram negative rods. Only useful against urinary tract pathogens, like E. coli, Staphylococcus saprophuticus, and Enterococcus spp.

Question 20

Daptomycin covers what bacteria?

Answer 20

MSSA, MRSA, Streptococci, and Enterococci

Question 21

Colistin covers what bacteria?

Answer 21

Gram negative rods and P. aeruginosa