spinal nerve roots Flashcards
(22 cards)
at 6 months of age the spinal cord terminates at what vertebral level
the conus medullaris is at the level of S1
describe the organisation of the spinal cord
8 cervical spinal nerve roots 12 throacic 5 lumbar 5 sacral and 1 coccygeal
in adulthood the conus medullaris is located at the level of
T12, L1 or L2
the cauda equina
are spinal nerve roots which contain no spinal cord but are surrounded in CSF and extend below L1/2
filum terminale
connective tissue in the centre of the cauda equina which projects from the conus medullaris and provides support to the spinal cord
intervertebral discs contain
a central nucleus pulposis and a disc annulus which absorb force and provide mobility
the ligamentum flavum and the posterior longitudinal ligaments are located where
posterior and anterior to the vertebral bodies, respectfully
the ligamentum flavum is prominent in cervical and lumbar regions and can contribute to nerve root compression when hypertrophied
for both cervical and lumbosacral disc herniations
the nerve root corresponds to the lower of the two nerve roots
the dermatome level for the nipples is
T4
dermatome for the umbilicus
T10
dermatome for the shoulder
C5
dermatome for the lateral arm including thumb and first digit
C6
middle finger dermatome
C7
dermatome for last two digits
C8
L4 and L5 represent the
anteromedial and anterolateral shin
define these terms: neuropathy, mononeuropathy, mononeuropathy multiplex, polyneuropathy, myelopathy, radiculopathy
neuropathy is a general term for nerve disorder
mononeuropathy suggests a focal neuropathy
mononeuropathy multiplex suggests a multifocal neuropathy
polyneuropathy suggests a generalised neuropathy and is common in diabetes and has a glove and stocking pattern of sensory loss, while mononeuropathies are fairly common also in diabetes
myelopathy suggests any spinal cord pathology which can be traumatic, inflammatory or degenerative
radiculopathy suggests a subtype involving the spinal nerve roots and is associated with a burning, tingling pain that radiates or shoots down a limb and is associated with disc protrusion, lateral recess stenosis, forminal osteophyte formation or spondylolithesis (fracture of the pars interarticularis)
disc protrusions can be graded in terms of degree of severity, name these grades
1- bulge
2- protrusion
3- extrusion - disc annulus has disintergrated
4- sequestration - loss of nucleus pulposis
Guilliane Barre Syndrome
is a type of peripheral neuropathy that is associated with progressive weakness and parasthesias, the patient is areflexic
there is an immune mediated demyelination of peripheral nerves and it occurs post a viral illness, Camphylobacter jejuni enteritis or HIV
CSF shows no cells and elevated protein
EMG studies prove demyelination
treatment involves plasmaphoresis and IV IgG, patient may need to be intubated and ventilated if the demyelination occurs in the trunk
Myasthenia gravis
is a neuromuscular junction disorder whereby immunoglobulins binds to actylcholine receptors on the motor end plate
the disease is characterised by symmetrical weakness of eyes, neck, proximal limbs and bulbar muscles (weakness is caused by fatigue)
all will have a nasal sounding voice, and there is usually dysphagia
15% may have extraocular involvement - ocular myasthenia
diagnosis - anticholinesterase antibodies, MuSK, EMG
20% will have thymoma and require thymectomy
Tx - anticholinesterase drugs, sometimes they may require plasmaphoresis, or IV IgG, or immunosuppressants
common disc herniations in the leg
1- L5,S1
2- L4,5
3- L3,4
common cervical radiculopathies
1- C6,7
2- C5,6
3- C4,5
cauda equina syndrome
impaired function of nerve roots below L1,L2
accompanied with urinary retention, saddle anaesthesia, incontienence, needs to be treated promptly
can be caused by disc herniation, local neoplastic disease ie schwannoma, meningioma, trauma, epidural abcess, arachnoiditis, cytomegalovirus polyradicultitis