Spinal Reflexes Flashcards

(38 cards)

1
Q

motor unit

A

single motor neuron and the muscle fiber that it innervates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

size principle

A

states that as motor units are recruited progressively a larger number of motor neurons are involved and greater tension will be generated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Type I (slow twitch fatigue resistant) fibers

A
  • many mitochondria and myoglobin present
  • slow contraction, little tension and high endurance
  • posture maintenance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Type IIb (fast twitch fatigable)

A
  • glycolytic (abundant glycogen)
  • large fiber diameter
  • fast contraction, high tension and low endurance
  • bursts of tension and precise movements
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Type IIa (fast twitch fatigue resistant)

A
  • mix between I and IIb
  • both oxidative and glycolytic
  • IIb fibers can develop into IIa fibers through training
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Henneman’s Size Principle

A
  • slow twitch fatigue resistant fibers are recruited first (type I)
  • fast fatigue resistance are recruited second (type IIa)
  • fast fatigable are recruited last (type IIb)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

during sustained activity, motor units will

A

cycle in rotation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

reflexes are

A

involuntary subconscious responses mediated by “hard-wired” pre-existing nerve circuits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

modulation of reflex activity

A

higher control signals are sent by interneurons to the motor nerves that control the reflex to modulate or change it (enhance or diminish)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

renshaw cells

A

type of interneuron located in the anterior horn of the spinal cord and are inhibitory for surrounding motor neurons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

anterior motor neurons

A
  • alpha (⍺-): for extrafusal muscle fibers
  • gamma (γ-): for intrafusal muscle fibers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

involuntary and voluntary motor control is modulated by the

A
  • spinal cord (involuntary)
  • higher brain centers (voluntary)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

intrafusal vs extrafusal muscle fibers

A
  • intra: too small to generate force (muscle spindles)
  • extra: generate force
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

gamma-motor neurons (Type Aγ)

A

innervate muscle spindle to sense muscle length (static) and rate of change (dynamic) and adjust to the sensitivity of the muscle spindle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

alpha-motor neurons (Type A⍺)

A

Innervate extrafusal muscle fibers that cause the muscle to contract and shorten, producing movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what does it mean that alpha- and gamma-motor neurons are co-activated

A

when the brain sends a movement signal, it activates both ⍺-motor neurons (extrafusal contraction) and γ-motor neurons (intrafusal adjustment) simultaneously

17
Q

why is co-activation important?

A
  • Prevents the muscle spindle from becoming slack during contraction, ensuring it remains sensitive to further changes in muscle length
  • Prevents the spindle from resisting movement, allowing smooth execution
  • Dampens unnecessary muscle oscillations, ensuring coordinated and precise movements
18
Q

Muscle spindles contain two types of specialized intrafusal length receptor muscle fibers

A
  • Nuclear Bag Fibers → phasic response
  • Nuclear Chain Fibers → static response
19
Q

Nuclear Bag Fibers (Dynamic, Phasic Response)

A
  • detect the velocity of changes in muscle length
  • highly compliant and quickly adapt to prolonged stretch
  • Innervated by Group Ia afferent neurons
  • Innervated by dynamic gamma-motor neurons, which have flower-spray endings and help regulate spindle sensitivity
20
Q

mechanism of nuclear bag fibers

A

when the muscle stretches, mechanoreceptors in the Ia afferents open sodium channels, leading to depolarization and signaling stretch to the CNS

21
Q

Nuclear Chain Fibers (Static Response)

A
  • detect sustained muscle length
  • innervated by Group II afferents, which provide tonic (sustained) sensory input about limb position, even when the limb is not moving
  • Innervated by static gamma-motor neurons, which have flower-spray endings to regulate sensitivity
  • innervated by group Ia afferent to providing continuous feedback about muscle length over time
22
Q

signal averaging function of the muscle spindle

A

the damping or smoothing out the stretch reflex that helps to prevent oscillation or jerkiness of body movements

23
Q

If the muscle spindle is not functioning correctly, then the muscle contraction is

A

jerky and not smooth during the course of a stimulus

24
Q

monosynaptic reflex

A
  • stretch, myotatic or jerk reflex
25
sequence of stimulation of monosynaptic reflex
1. When muscle is stretched, group Ia afferents are activated and firing increases. 2. Group Ia synapse on alpha-motor neurons and these alpha-motor neurons innervate the extrafusal fibers of homonymous muscle. 3. The alpha-motor neurons will cause contraction which will shorten both the intra- and extra-fusal fibers Group Ia afferents return to baseline. 4. While there is contraction of synergistic muscles, the antagonistic muscles will relax.
26
what are the 3 neural circuits that can modulate monosynaptic reflex
- reciprocal innervation - renshaw arc - gamma efferents
27
reciprocal innervation
when interneurons activate synergistic muscles and at the same time the antagonist muscles are inhibited by the interneuron releasing glycine to increase chloride conductance
28
renshaw arc
alpha-motor neurons can activate Renshaw cells causing feedback inhibition that will inhibit other parallel motor nerves as well as the primary motor neuron by releasing inhibitory neurotransmitters, GABA and glycine
29
Function of Renshaw arc is to
confine reflex to one group of muscles without interference from other muscle groups that will prevent an over-exuberant response (i.e., muscle spasticity).
30
Baclofen
an agonist for the GABA type B receptor used in the treatment of muscle spasticity
31
multi-synaptic reflex
Golgi Tendon reflex (feedforward inhibition) and withdrawal reflex
32
primary and secondary function of the golgi tendon reflex
- primary: equalize muscle tension between agonist and antagonist muscles across a joint - secondary: to prevent the muscle and/or tendon from tearing from within or from bone due to rapid induced high levels of muscle tension
33
flexor-withdrawal reflex is the motor response to
protopathic stimuli that causes the perception of pain
34
crossed extensor reflex
On the contralateral side of spinal cord (opposite side of pain stimulus), the flexor muscles are inhibited, and the extensor muscles are stimulated to contract.
35
what CNS circuits are present in the withdraw reflex
- divergence - reciprocal inhibition - after discharge
36
Afterdischarge is the continued rate of
flexor contraction due to recurrent pathways
37
Central pattern generators (CPGs) have
patterns of repetitive and alternating activity
38
Initiation and control of CPGs originates in
- Motor cortex for initiation - Basal ganglia for maintaining the repetitive movement