Spirochetes and Chlamydia Flashcards

(63 cards)

0
Q

Local nontender ulcer (chancre) in the genitals that forms in 2-10 weeks

A

Primary Syphilis

T pallidum

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1
Q

Microphilic bacteria that lacks TCA

A

Treponema pallidum

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2
Q

Condyloma lata, maculopapular rash at palms soles and feet, fever, headache, malaise, anorexia and lymphadenopathy after 1-3 months

A

Secondary syphilis

T pallidum

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3
Q
Granulomas (gummas)
Neurosyphilis
- tabes dorsalis: argyll robertson pupil or prostitute's pupil
- dementia paralytica
Aortitis from endarteritis
A

Tertiary syphilis

T pallidum

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4
Q

Condyloma acuminata

Condyloma lata

A

HPV

T pallidum

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5
Q

Aortitis from endarteritis

Aortitis in the coronary artery

A

T pallidum

Kawasaki

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6
Q
Snuffles/saddle nose
Mulberry molars
Hutchinson triad: hutchinson teeth, deafness, keratitis
Saber shins
Rhagades (whitish lesions on the mouth)
Positive Higoumenaki's sign (unilateral enlargement to detachment of sternoclavicular portion of clavicle)
Clutton's joints (synovitis)
Pulmonary hemorrhage
A

Congenital syphilis

T pallidum

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7
Q

Diagnostic test for primary syphilis

A

Dark field microscopy

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8
Q

Diagnostic test for secondary and tertiary syphilis

A

RPR/VDRL for screening

FTA-ABS for confirmation

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9
Q

Gummas

A

Tertiary syphilis

T pallidum

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10
Q

False positive results for VDRL

A

Viruses EBV, hepatitis
Drugs marijuana
Rheumatic fever, rheumatoid arthritis
Lupus, leprosy

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11
Q

Tabes dorsalis

A

Neurosyphilis
Tertiary syphilis
T pallidum

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12
Q

Influenza like symptoms a few hours after receiving penicillin for syphilis

A

Jarisch Herxheimer reaction

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13
Q

Argyll Robertson pupil

Prostitute’s pupil

A

Tabes dorsalis
Neurosyphilis
Tertiary syphilis
T pallidum

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14
Q

Largest medically important bacteria

A

Borrelia burgdoferi

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15
Q

Dementia paralytica

A

Neurosyphilis
Tertiary syphilis
T pallidum

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16
Q

Aniline dyes

Giemsa or Wright stain

A

Borrelia burgdorferi

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17
Q

Mulberry molars

A

Congenital syphilis

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18
Q

From white footed mouse and white tailed deer

Deer ticks - Ixodes scapularis

A

Borrelia burgdoferi

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19
Q

Hutchinson triad

A

Hutchinson teeth
Keratitis
Deafness

Congenital syphilis
T pallidum

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20
Q

Deer ticks - Ixodes scapularis

A

Borrelia burgdorferi

Babesia microti

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21
Q

Saber shins

A

Congenital syphilis

T pallidum

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22
Q

Lyme disease

A

Borrelia burgdorferi

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23
Q

Whitish lesions at the angle of the mouth

A

Rhagades
Congenital syphilis
T pallidum

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24
Erythema migrans | Target lesions
Stage 1 Lyme disease | Borrelia burgdorferi
25
Higoumenaki's sign
Unilateral enlargement to detachment of the sternoclavicular portion of the clavicle Congenital syphilis T pallidum
26
Myocarditis (AV block), Meningitis, Bell's palsy
Stage 2 Lyme disease | Borrelia burgdorferi
27
Autoimmune migratory polyarthritis - onion skin lesions | Acrodermatitis chronica atrophicans - atrophy of the skin and hands
Stage 3 Lyme disease | Borrelia burgdorferi
28
Clutton's joints - synovitis
Congenital syphilis | T pallidum
29
Acrodermatitis enteropathica
Skin ulcers and poor wound healing secondary to zinc deficiency
30
Pulmonary hemorrhage
Weil's disease Anthrax Congenital syphilis
31
DOC for early localized or disseminated Lyme disease
Doxycycline
32
DOC for late Lyme disease
Penicillin or Ceftriaxone
33
Relapsing fever | Undulating fever
Borrelia recurrentis | Brucella abortis
34
Diagnostic of choice for Borrelia recurrentis
Microscopy
35
Drug of choice for Borrelia recurrentis
Tetracycline or Erythromycin
36
Vector for Borrelia recurrentis
Pediculus humanus
37
Shepherd's crook
Hook at one or both pointed ends | Leptospira interrogans
38
EMJH or Fletcher's medium
Leptospira interrogans
39
Organisms found in _ during early Leptospirosis and _ during late Leptospirosis
Blood and CSF | Urine
40
Gold standard for diagnostics of Leptospirosis
LeptoMAT
41
Calf tenderness | Conjunctival suffusion
Acute leptospiremic phase | L interrogans
42
Aseptic meningitis that coincides with appearance of antibody titers Hepatic necrosis Glomerulonephritis
Immune leptospiruric phase
43
Snow flake lesions in CXR
Immune leptospiruric phase
44
Triad of Weil Syndrome
Jaundice Bleeding Uremia
45
Orange cast skin
Weil Syndrome
46
DOC for Leptospirosis
Penicillin G
47
Cell wall lacks muramic acid
Chlamydia trachomatis
48
Cycloheximide culture
Chlamydia trachomatis
49
Halberstadter-Prowazek inclusions in Giemsa
Round to oval cytoplasmic inclusion bodies near the nuclei of connunctival epithelial cells in trachoma Chlamydia trachomatis
50
Most common STD
C trachomatis D-K Neonatal conjunctivitis and pneumonia Reiter's syndrome
51
Two forms of Chlamydia
Elementary body - Enactive, Extracellular, Endocytosis | Reticulate body - active, intracellular, seen microscopically
52
Trachoma Types A B C
Africa Blindness Chronic infection
53
Papule or vesicle which ulcerates and leads to suppurative inguinal lymphadenopathy Positive Frei test
Buboes in Lymphogranuloma Venereum | C trachomatis L1-L3
54
Buboes
Yersinia | Chlamydia
55
Sudden onset pneumonia with malaise, fever, anorexia, sore throat, photophobia, and severe HA after bird exposure
Bird fancier's disease Psittacosis C psittaci
56
DOC for Chlamydia | STD
Azithromycin
57
DOC for Chlamydia | Conjunctivitis
Erythromycin
58
DOC for Chlamydia | LGV
Doxycyxline
59
DOC for Chlamydia | Psittacosis
Azithromycin
60
Associated with atherosclerosis
C pneumoniae
61
Only disease diagnosed by demonstration of spirochetes in peripheral blood smear
Relapsing fever
62
Treponemal test
VDRL