Spring Top 300 Drugs Flashcards
(130 cards)
1
Q
Which of the following is the pharmacological class for hydroxyzine?
A
antihistamine
2
Q
Which of the following is an FDA-approved indication for clobetasol?
A
Plaque psoriasis
3
Q
Does alendronate require dose adjustment for hepatic impairment?
A
No
4
Q
Which is a pharmacologic class of adapalene?
A
Retinoid
5
Q
One of the FDA-approved indications for meclizine is
A
Vertigo
6
Q
What is the brand name of dulaglutide?
A
Trulicity
7
Q
What is the mechanism of action for fexofenadine?
A
Selective H-1 Receptor Antagonist
8
Q
The mechanism of action of clindamycin topical is to inhibit bacterial protein synthesis by binding to which of the following ribosomal subunits?
A
50S
9
Q
Which of the following is a major adverse drug reaction for ibandronate?
A
Indigestion
10
Q
Which of the following is a major adverse drug reaction of cetirizine?
A
Drowsiness
11
Q
By inhibiting _____, amiodarone may increase the risk of hypoglycemia when combined with glimepiride.
A
CYP2C9
12
Q
What is the mechanism of action for linagliptin?
A
Prolongs incretin levels
13
Q
Metformin works by
A
Reducing hepatic glucose production
14
Q
Which of the following is a major adverse drug reaction for glipizide?
A
Disulfiram reaction
15
Q
Which of the following is a major adverse drug reaction of liraglutide?
A
Renal failure
16
Q
Which is the pharmacologic class of insulin glargine?
A
Long-acting insulin
17
Q
What is the brand name of insulin lispro?
A
Humalog
18
Q
What is the brand name of insulin aspart
A
Novolog
19
Q
What is the generic name of Afrezza?
A
Inhaled insulin
20
Q
What is the generic name of Apidra?
A
Insulin glulisine
21
Q
Which of the following is the pharmacological class for repaglinide?
A
Meglitinide
22
Q
Which one of the following is LEAST likely to be involved in CYP450 mediated drug-drug interactions?
A
Dexlansoprazole
23
Q
The brand name for rosiglitazone is
A
Avandia
24
Q
Which is a pharmacologic class of dicyclomine?
A
Antimuscarinic
25
Which of the following is an FDA-approved indication for dutasteride?
Benign Prostatic Hyperplasia
26
What is the brand name of saxagliptin?
Onlgyza
27
What is the mechanism of action for famotidine?
H2 antagonism
28
Pioglitazone works by
Increasing insulin sensitivity
29
Which of the following is a major adverse drug reaction for sitagliptin?
Rhabdomyolysis
30
Is renal dosing adjustment required for canagliflozin?
Yes
31
Which of the following is the pharmacological class for phenazopyridine?
analgesic
32
Which of the following is an FDA-approved indication for darifenacin?
Overactive bladder
33
The brand name for pentosan is
Elmiron
34
Which is a pharmacologic class of polyethylene glycol?
Hyperosmotic laxative
35
Which of the following is an FDA-approved indication for omeprazole?
Erosive esophagitis
36
What is the brand name of rabeprazole?
AcipHex
37
What is the mechanism of action for oxybutynin?
Muscarinic Receptor Antagonist
38
Lubiprostone works by
Activating chloride channels
39
Does ranitidine require dose adjustment for renal dysfunction?
Yes
40
A patient taking metoclopramide with Phenergan would be at greater risk of ___________ compared to a patient taking either drug alone.
Tardive dyskinesia
41
Which of the following is the pharmacological class for tolterodine
Antimuscarinic
42
Which one of the following medications is LEAST likely to decrease tamoxifen activation?
Effexor
43
The brand name for ethinyl estradiol/etonogestrel is
NuvaRing
44
Which is a pharmacologic class of anastrozole?
Aromatase Inhibitor
45
Which of the following is an FDA-approved indication for darbepoetin?
Anemia of CKD
46
Does epoetin require hepatic dose adjustment?
No
47
Cyanocobalamin works by acting as a cofactor for ________ synthesis.
Amino acid
48
Tamsulosin works through ___________ of _____ receptors.
Inhibition; alpha-1
49
Which of the following is an adverse drug reaction for estradiol?
Venous thromboembolism
50
Which of the following is a major adverse drug reaction of epinephrine?
Pulmonary edema
51
Which of the following is the FDA-approved indication for folic acid?
Megaloblastic anemia
52
Which of the following is a major adverse effect of intranasal fluticasone?
Glaucoma
53
The brand name for fluocinonide is __________.
Vanos
54
Does methylprednisolone require renal dose adjustment?
No
55
One of the FDA-approved indications for topical hydrocortisone is __________.
Atopic Dermatitis
56
What is the mechanism of action for medroxyprogesterone?
It transforms proliferative into secretory endometrium
57
What is the pharmacologic class of Aranelle?
Triphasic oral contraceptive
58
The presumed mechanism of action of mometasone is induction of what?
Phospholipase A2 inhibitory proteins
59
Which of the following is a major adverse reaction of levothyroxine?
Hyperthyroidism
60
Drospirenone/ethinylestradiol is also known by which brand name?
Yasmin
61
The dose of Cialis should be reduced when administered concurrently with:
Biaxin
62
Triamcinolone Nasal has an FDA indication for which of the following disease states?
Allergic Rhinitis
63
Which of the following is the pharmacological class of prednisone?
Adrenal corticosteroid
64
Which of the following describes the mechanism of action of raloxifene?
Selectively binds to estrogen receptors
65
An adverse effect of Armour Thyroid is the aggravation of preexisting what type of disease?
Cardiovascular
66
Which of the following is a brand name for the pertussis vaccine?
Boostrix
67
Which of the following is/are involved in the mechanism of action of etanercept?
TNF alpha
68
What is the pharmacological class of sildenafil?
Pulmonary hypertension agent
69
Is hepatic dose adjustment required for testosterone?
No
70
Which of the following is an adverse drug reaction to the pneumococcal vaccine?
Myalgia
71
What is the brand name for Baclofen?
Lioresal
72
The combined use of apomorphine and Zofran is contraindicated due to:
Additive hypotension
73
Which of the following is an FDA approved indication for carbamazepine?
Trigeminal neuralgia
74
Inhibition of phosphodiesterase type 5 to increase the amount of cyclic GMP is the mechanism of action of which drug?
Vardenafil
75
Which of the following is a major adverse effect of promethazine?
Xerostomia
76
Is renal dose adjustment recommended for tizanidine?
Yes
77
Nabumetone belongs to which pharmacological class?
NSAID
78
Which of the following is an FDA approved indication for methocarbamol?
Musculoskeletal spasm
79
What is the mechanism of action of carbidopa in carbidopa/levodopa?
It inhibits decarboxylation of levodopa to allow more to reach the CNS
80
Which of the following is a major adverse drug reaction of cyclobenzaprine?
Drowsiness
81
Which of the following is the proposed mechanism of action for clobazam?
Potentiation of neurotransmission from binding at the GABA receptor
82
Which of the following is an FDA-approved indication for divalproex?
Migraine prophylaxis
83
Which of the following is the brand name for donepezil?
Aricept
84
Which of the following is a major adverse drug reaction to lamotrigine?
Diplopia
85
Is renal dose adjustment recommended for oxcarbazepine?
Yes
86
A proposed mechanism of action of eletriptan is that it produces vasoconstriction through the activation of which intracranial receptors?
Serotonin
87
Which of the following types of seizures is an FDA-approved indication for lacosamide?
Partial onset
88
What is the generic name for Namenda?
Memantine
89
Patient TF has been started on phenytoin for treatment of epilepsy. This is the patient's first treatment for epilepsy and they have only been on phenytoin for 2 weeks and are still having seizures daily. Patient is also currently on apixaban for stroke prophylaxis. A consult was placed to have pharmacy look at the patient's medications and make their recommendation. Which of the following is the BEST answer regarding modifying this patient's medication therapy?
Change the patient's epilepsy medication, potentially to Keppra
90
Which of the following is a major adverse drug reaction to sumatriptan?
Cardiac dysrhythmia
91
Cyclosporine inhibits the production of which interleukin?
2
92
Which of the following is an FDA-approved indication for loteprednol?
Postoperative inflammation
93
Is renal dose adjustment recommended for topiramate?
Yes
94
Which of the following is the generic name for lumigan?
Bimatoprost
95
Which of the following is a major adverse reaction to celecoxib?
Hypertension
96
What does moxifloxacin ophthalmic inhibit as part of its MOA?
Topoisomerase II
97
Which of the following is the FDA-approved indication for olopatadine?
Allergic Conjunctivitis
98
Which of the following is the pharmacological drug class for travoprost?
Prostaglandin
99
What is the brand name of latanoprost?
Xalatan
100
The analgesic effects of which one of the following will be reduced if taken together with a strong CYP2D6 inhibitor?
Codeine/APAP
101
Which of the following is a major adverse drug reaction for diclofenac?
Acute renal failure
102
What is the brand name for etodolac?
Lodine
103
Which of the following is an FDA-approved indication for ibuprofen?
Fever
104
Which of the following vaccines should be avoided in a patient being treated with a TNF-alpha inhibitor?
Varivax
105
Which of the following does Meloxicam inhibit as part of its mechanism of action?
COX-1 and COX-2
106
Which of the following is a major adverse drug reaction of hydrocodone?
Constipation
107
What is the pharmacological class of the lidocaine topical patch?
Local anesthetic
108
Is hepatic dose adjustment required for methadone?
No
109
Which of the following is an FDA-approved indication for Kadian?
Moderate to severe chronic pain
110
What is the brand name for naproxen?
Naprosyn
111
What is the pharmacological class of Tramadol?
Opioid
112
What is the generic name for Abilify?
Aripiprazole
113
The mechanism of action for benztropine involves inhibiting reuptake and storage of what?
Dopamine
114
Which of the following is an FDA-approved indication of prochlorperazine?
Anxiety
115
Which of the following is a major adverse drug reaction to Lithium?
Hypothyroidism
116
Are there hepatic dose limitations for citalopram?
Yes
117
What is the brand name for buspirone?
Buspar
118
Which of the following is an FDA-approved indication for lurasidone?
Schizophrenia
119
Desvenlafaxine is a potent reuptake inhibitor of what?
Norepinephrine
120
Metabolic clearance of which of the following will be affected by smoking tobacco?
Zyprexa
121
Which one of the following is LEAST likely to be involved in CYP450 mediated drug-drug interactions?
Ziprasidone
122
What is the generic name for Harvix?
Hepatitis A Vaccine
123
Which of the following is an FDA-approved indication for tacrolimus?
Liver transplant rejection
124
Which of the following is a major adverse drug reaction to the influenza vaccine?
Which of the following is a major adverse drug reaction to the influenza vaccine?
125
Risperidone is a potent antagonist of what?
Serotonin
126
Which of the following is an approved FDA indication of Recombivax HB?
Prevention of Hepatitis B infection
127
Is renal dosage adjustment required for quetiapine?
No
128
Which of the following is the pharmacological class for the HPV vaccine?
Vaccine, Inactivated, Viral
129
Which of the following is a brand name for Haemophilus Influenzae Type B Vaccine?
Hiberix
130
Which of the following is an approved FDA-indication of potassium iodide?
Prevention of thyroid dysfunction due to radiation exposure
