Squamous Cell Carcinoma Flashcards
Co factors for aq.c.c?
- age
- gender
- race
- geography
- friction
- chronic diseases
- hormones
Sites of peripheral sq.c.c
Tumors arise in soft tissues. • Any area of oral cavity may be affected but
The most common sites are: E 1. Lateral side of posterior 3rd of tongue.
- Floor of mouth.
- Soft palate.
- Anterior 3rd of tongue. 5. Lower lip > upper lip (upper more
dangerous) .
Central location of Square.c.c
Max sinus
Metastasis in blood for sq.c.c
Very late
Patient dies first
Lymphatic spread of sq.c.c
In 21% of initially diagnosed cases
Into regional lymph nodes
Does socioeconomics affect diagnosis of sq.c.c
Yes
4-8 months in high socioeconomics. o 8-24 months in low socioeconomics.
D.D. of ulcer with rolled borders?
: 1. Chronic traumatic ulcer..
2.
Deep fungal ulcer.
- TB ulcer.
4.
Syphilitic ulcer.
Shape of sq.c.c may be:
- White patch (leukoplakia).
21 Red patch (erythroplakia).
- Speckled leukoplakia.
4.
5.
Exophytic growth which is hard and
indurated.
Endophytic growth (ulcer).
Criteria of malignant ulcer?
i. Persistent (long standing) ulceration. 11. Induration and fixation of the affected
tissue to the underlying structure. ii. Raised, rolled everted edges.
Bloody discharge or crusted.
Irregular outline.
Necrotic floor with foul odor.
Grade of verrucous carcinoma
A rare low grade variant of oral SCC.
• Epidemiology 1% to 10% of all oral SCC.
Site of verrucous carcinoma?
At the site of chronic tobacco placement (mandibular vestibule, the buccal mucosa and the palatal mucosa).
May be extraoral at skin & lip (not due to tobacco chewing).
Verrucous carcinoma is low grade why?
-doesnot errode neighbouring structure early
-regional lymph node if large are just infected
Metastasis is not common
-slowly growing
Shape of verrucous carcinoma?
- wharty
- plaque
- deep clefts between its papilla
- white
- could be red acc. To inflammation and keratosis
