SQUAMOUS PAPILLOMA

Question 1

CONCEPT

Answer 1

BENIGN PAPILLARY/VERRUCIFORM MASS RESULTED FROM HPV-INDUCED PROLIFERATION OF STRATIFIED SQUAMOUS EPHITELIUM

Question 2

CAUSE

Answer 2

HPV TYPES 6 AND 11

Question 3

INTRAORALLY

Answer 3

• ANY SURFACE AFFECTED (MOST COMMON PALATE, TONGUE, LIPS)
• SOFT, ASYMPTOMATIC, PINK TO WHITE EXOPHYTIC NODULE OR CAULIFLOWER-LIKE APPEARANCE WITH MULTIPLE FINGER- LIKE PROJECTIONS/SOLITARY/MULTIPLE LESIONS MAY OCCUR

Question 4

TREATMENT

Answer 4

CONSERVATIVE EXCISION INCLUDING THE BASE OF THE LESION

Question 5

HISTOLOGICALLY

Answer 5

CELLS “KOILOCYTES” PRESENT IN THE SPINOUS CELL LAYER OF SQUAMOUS PAPILLOMA AND VERRUCA VULGARIS. THEY ARE VIRUS ALTERED EPITHELIAL CELLS WITH CRNATED, PYKNOTIC NUCLEI AND PERINUCLEAR CLEARING