SSc, Polymyositis, Dermatomyositis Flashcards
(38 cards)
1
Q
A
Calcinosis Raynauds Esophageal involvement (+gut dysmotility) Sclerodactyl Telangectasia
2
Q
A
face hands and feet
3
Q
A
pulmonary hypertension
4
Q
A
Anti-centromere
5
Q
A
The whole body
6
Q
A
Lung
Cardiac
GI
Renal
7
Q
A
Echocardiogram
spirometry
8
Q
A
Anti-topoisomerase-1 (40%) (aka Scl70)
9
Q
A
anti-RNA polymerase
10
Q
A
increases the risk of renal crisis
11
Q
A
AKI
Accelerated hypertension
12
Q
A
ACEi
A2RBs
13
Q
A
Stop smoking
14
Q
A
Reactive hyperaemia (the worst!)
15
Q
A
Nifedipine
Sildenafil
16
Q
A
IV prostacyclin
17
Q
A
sympathectomy
18
Q
A
cyclophoshamide
19
Q
A
cartilage
20
Q
A
Pinna
nasal septum
larynx (stridor)
21
Q
A
T
22
Q
A
insidious
23
Q
A
striated
24
Q
A
proximal
25
[Polymyositis]: AI muscle weakness can affect those in the neck causing (2)
dysphonia
| Dysphagia
26
[Dermatomyositis]: If dermatomyositis the inflammed muscle is likely to be from what cause
paraneoplastic
27
[Dermatomyositis]: What is the difference between poly and dermato
Skin involvement
28
[Dermatomyositis]: Which 3 places would you especially look for a rash
Shawl sign (back and shoulders)
Eyelids (lilac-purple with oedema)
Knuckles (papules, also elbows knees)
29
[-myositis]: fever, arthralgia and raynauds may be present. What disease can affect the lung
Interstial
| also breathing difficutlies due to muscle damage
30
[-myositis]: What is inflammation of the heart muscle called
Myocarditis
31
[-myositis]: What is the golden Ix
Muscle biopsy
32
[-myositis]: name 5 muscle enzymes which may be raised
```
ALT
AST
Aldolase
CK
LDH
```
33
[-myositis]: What 2 antibodies are associated
Anti-Mi2
| Anti-Jo1
34
[-myositis]: what is important to remember before you decide to treat just the myositis
Screen for malignancy. It can be paraneoplastic.
35
[-myositis]: 1st line Tx is ...
Prednisolone
36
[-myositis]: In resistance cases .. may be used at Tx
immunosuppresives (aziathiproine/methe/cyclophos)
37
[-myositis]: What 2 drugs may help with the skin changes
Hydroxychloroquine
| tacrolimus
38
[-myositis]: Subcutaneous .... deposits may also be present
calcium
