SSRI’S

Question 1

Ssri’s

Answer 1

Selectively reuptate serotonin in the synaptic space. Thereby intensify the effects of serotonin

Question 2

Ssri’s

Answer 2

First line of pharmacological treatment for depression - months to show benefit months to show full therapeutic effect

Question 3

Ssri’s

Answer 3

May increase the level of energy before mood.

Question 4

Ssri’s side effects

Answer 4

Nausea, vomiting, diarrhea, weight loss, headache, sexual dysfunction (erectile disfunction ,sexual desire, difficulty reaching orgasm)

Question 5

Ssri increase the risk for bleeding if they are taken with what medication?

Answer 5

NSAID’s, aspirin, warfarin, and other blood thinners

Question 6

Ssri’s approved by FDA to treat
depression?

Question 7

CITALOPRAN

Answer 7

CELEXA

Question 8

ESCITALOPRAM

Answer 8

LEXAPRO

Question 9

FLUOXETINE

Answer 9

PROZAC

Question 10

PAROXETINE

Answer 10

PAXIL - PEXEBA

Question 11

SERTRALINE

Answer 11

ZOLOFT

Question 12

SNRI’S

Answer 12

Selectively block the uptake ofNOREPINEPHRINE and SERATONIN, intensifying the effect of neurotransmitters

Question 13

WHAT ARE THE SIDE EFFECTS OF SNRI’S?

Answer 13

Nausea, sweating, insomnia, tremors, sexual dysfunction

Question 14

SNRI’S approved by the FDA

Question 15

DESVENLAFAXINE

Answer 15

PRISTIQ

Question 16

DULOXETINE

Answer 16

CYMBALTA (also used for anxiety and chronic pain)

Question 17

LEVOMILNACIPRAN

Answer 17

FETZIMA

Question 18

VENLAFAXINE

Answer 18

EFFEXOR XR- also approved to treat certain anxiety and panic disorders

Question 19

ATYPICAL ANTIDEPRESSANTS

Answer 19

Change levels of 1 or more neurotransmitters.
Dopamine
SERATONIN
Norepinephrine

Question 20

ATYPICAL ANTIDEPRESSANTS APPROVED BY THE FDA

Question 21

BUPROPION.

Answer 21

Low risk for sexual dysfunctions, and weight gain, lower threshold of seizures. Not recommended for ppl with history of head injury , seizure or eating disorder-

Wellbutrin SR,
-Wellbutrin XL
- Nefazodone
-Trazodone

Question 22

VILAZODONE

Answer 22

Viibryd

Question 23

VORTIOXETINE

Answer 23

Trintellix

Question 24

MIRTAZAPINE

Answer 24

Increases appetite
—Beneficial for those with low intake
-weight gain
- fatigue
-elevated cholesterol

Question 25

TRAZODONE

Answer 25

In combination with SSRI treats insomnia, side effects of sedation are rare( prolonged erection of penis)

Question 26

TRICYCLIC ANTIDEPRESSANTS - TCAs

Question 27

Adverse effects of TCA’S

Answer 27

Anticholinergic effects -orthostatic hypotansion -sedation -arrhythmia -tachycardia Lethal toxicity - OD - Excessive sweating -Increase appetite/ weight gain - Sexual dysfunction

Question 28

TCA’S are CONTRAINDICATED/ PRECAUTIONS for:

Answer 28

- Seizure disorder -CAD -Diabetes - Urinary retention -HIGHLY TOXIC, ASSESS OD - MAY INCREASE SUICIDE RISK

Question 29

TCA’S approved by the FDA

Question 30

AMYTRIPTYLINE

Question 31

AMOXAPINE

Question 32

DESIPRAMINE

Answer 32

NORPRAMIN

Question 33

DOXEPIN

Question 34

NORTRIPTYLINE

Answer 34

Pamelor

Question 35

TCA’S treat……

Answer 35

-Depression - OCD - Anxiety - Neuropathy

Question 36

WHEN TO TAKE TCA’S ?

Answer 36

At bed time because of drowsiness

Question 37

TCA’S that cause weight gain

Answer 37

-amitryptyline -doxepin -I I-famine -trimipramine

Question 38

WHAT TCA’S ARE MORE TOLERATED

Answer 38

-NORTRYPTYLINE -DESIPRAMINE

Question 39

MONOAMINE OXIDASE INHIBITORS (MAOI’s)

Answer 39

Increases : Norepinephrine -dopamin -SERATONIN

Question 40

WHAT ARE THE RISKS FOR MAOI’s

Answer 40

Hypertensive crisis -Orthostatic Hypotension - Require a 14 day washout

Question 41

TCA’S interactions and contraindications

Answer 41

-SSRI’s -TCA’S -SSRI’s -OTC decongestants -Antihypertensive - Amphetamines and caffeine - HF and CVD - Renal disease, pheochromocytoma, irregular secretion of epinephrine and norepinephrine - IncreasesBP, palpitations and HA

Question 42

MAOI’S APPROVED BY THE FDA

Question 43

ISOCARBOXACID

Answer 43

MARPLAN

Question 44

PHENELZINE

Answer 44

Nardil

Question 45

SELEGILINE

Answer 45

Emsam

Question 46

TRANYLCYPROMINE

Answer 46

PARNATE

Question 47

ALL ANTIDEPRESSANTS CARRY A BLACK BOX WARNING FOR INCREASE RISK OF SUICIDE IN CHILDREN, ADOLESCENTS, AND YOUNG ADULTS SPECIALLY THE FIRST FEW WEEKS AFTER STARING , OR WHEN THE DOSE HAS CHANGED.