SSRIs Flashcards

(73 cards)

1
Q

Which 2 medications are FDA approved for PTSD, OCD, and GAD

A

Paroxetine and sertraline

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2
Q

Which SSRIs cause QT prolongation

A

Paroxetine
Citalopram
Escitalopram (not as bad)
Fluoxetine
Fluvoxamine

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3
Q

Which SSRIs do not cause QT prolongation

A

Sertraline

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4
Q

Which SSRIs are weight neutral/loss?

A

Sertraline
Fluoxetine

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5
Q

Which SSRIs can be used post CABG

A

Escitalopram

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6
Q

Which SSRIs are good for kidneys?

A

Sertraline
Fluoxetine

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7
Q

Which SSRI causes weight gain?

A

Paroxetine

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8
Q

What SSRIs are activating?

A

Escitalopram and fluoxetine

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9
Q

Which SSRI has less bad sexual side effects?

A

Escitalopram (Lexapro)

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10
Q

Which SSRI has a shorter half life but less sexual side effects?

A

Escitalopram

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11
Q

Which SSRI has a very long half life, making it better for noncompliant, but has bad sexual side effects

A

Fluoxetine

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12
Q

What are the benefits of trintellix?

A

Mental clarity
Safe
No QT prolongation

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13
Q

What labs should be checked for SSRIs?

A

Sodium (SIADH
LFT
Baseline kidney

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14
Q

What do you need to worry about with SNRIs?

A

BP
Not kidney safe
QT prolongation

Maybe more effective but worse withdrawal, can cause suicidality

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15
Q

What are effects of SNRIs

A

Activating but can cause insomnia

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16
Q

What is the benefit of bupropion?

A

Dopaminergic, can help with treatment resistant depression, ADHD, activating

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17
Q

What can bupropion cause?

A

insomnia

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18
Q

Does bupropion have QT prolongation or weight gain?

A

No

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19
Q

Sexual side effects of bupropion

A

none
can be added to medications that have

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20
Q

What are the anxiolytics?

A

Buspar
Hydroxyzine penoate
Doxipin
Benzos

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21
Q

What are the indications for buspar?

A

Benzo naive anxiolytic
TRD

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22
Q

SE of buspar

A

Headache

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23
Q

What can buspar be used for in conjunction with other meds?

A

Offset sexual side effects

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24
Q

Does buspar cause weight gain?

A

No

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25
What do you have to be careful with hydroxyzine for?
Potent QT Can cause to be sleepy
26
What is doxipin used for?
Panic disorder or depression Sleep (can be PRN)
27
What are the short acting benzos
Alprazolam (Xanax)
28
What are the moderate acting benzos
Lorazepam (Ativan)
29
What are the long acting benzos
Clonazepam (clonipin) Diazepam (Valium)
30
What is librium used for?
Alcohol withdrawal
31
What are the mood stabilizers?
Lithium Lamotrigine Depakote Carbazepine Oxcarbazepine
32
What 2 mood stabilizers do you need to check levels of?
Lithium and valproic acid
33
What are risks of lithium?
lithium toxicity Thyroid and kidney toxic
34
What are risks of lamotrigine?
SJS, well tolerated at low levels Social dysfunction at high
35
What is depakote (valproic acid) also used for?
Bipolar disorder with anger
36
Risks of depakote use
Wrecks liver and valproic acid toxicity
37
What is carbazepine and oxcarbazepine good for?
Anger (chronic pain oxcarbazepine)
38
What are the antipsychotics
Haldol Risperdol Paloperidone Olanzapine Aripiprazole Quetiapine Zyprazidone/geodon
39
What is the 1st generation antipsychotics
Haldol
40
Which antipsychotics have LAI
Risperdal Paloperidone Aripiprazole/abilify
41
What are side effects of haldol, risperdal, and paloperidone
extrapyramidal symptoms tardive dyskinesia diabetes mellitus hyperlipidemia anticholinergic weight gain flat affect "haldol shuffle"
42
what would you use haldol/risperdal for?
schizophrenia/schizoid or severe bipolar
43
what is the benefit of olanzapine?
Less EPS symp (still poss) Good for anger
44
What is aripiprazole (abilify) used for?
Treatment resistant depression mood stabilization psychosis with schizophrenia
45
side effects of aripiprazole
no weight gain, not as much EPS
46
What is quetiapine used for at low doses?
insomnia
47
what are side effects of quetiapine?
weight gain dm hyperlipidemia hypotension QT prolongation Anxiolytic at low doses
48
Which medication requires you to eat 350 calories at the same time as the med?
Geodon
49
Geodon/ziprasidone and latuda are _______ at low doses
activating
50
vraylar is cleaner (doesn't cause QT prolongation, sexual SE, or flat affect) but it does have a tendency to cause _______
akathisia
51
Indications for ryxalty
TRD Schizophrenia
52
What are risks of clozaril?
Blood dyscrasia Agranulomatous cytosis
53
What are the sleep meds?
Melatonin Diphenhydramine Hydroxyzine HCl Mirtazapine Doxipen Nortriptyline/amitryptiline Trazodone Rozerem Seroquel Z drugs Tamazepam
54
how much melatonin is usually required to work
9-10 mg
55
which sleep med is a potent QT prolongation agent
diphenhydramine
56
which sleep med is similar to a TCA, induces sleep at lower doses and is activating at higher doses
mirtazapine
57
Is mirtazapine kidney safe?
Yes
58
What are adverse effects of mirtazapine
weight gain
59
what is doxipen used for?
Sleep maintenance
60
what conditions can doxipen be used as an adjunct for?
panic disorder pain TRD
61
What is the MOA of trazodone
blocks serotonin 2a receptors and reuptake pump
62
Which medication works on melatonin receptors?
Rozerem
63
What sleep medication can cause QT prolongation and dyslipidemia?
Seroquel/quetiapine
64
What are the z drugs?
Ambien/zolpidem Lunesta Belsomra
65
What is the benzo that is only for sleep?
Tamazepam
66
What is an adverse side effect of clonidine?
Rebound hypertension and hypotension if normal BP
67
What are the nightmare meds?
Clonidine Topiramate Ceproheptidine Prazosin
68
What can clonidine be used for outside of nightmare?
ADHD opiate withdrawal
69
What needs to be watched for with topiramate?
weight loss
70
what can topiramate cause at high doses?
brain fog
71
topiramate can be used for what outside of nightmare?
alcohol withdrawal
72
What can ceproheptidine cause?
Weight gain
73
What medications are used for cravings?
Natrexone and acamprosate