Staging Flashcards
(15 cards)
What is stage I HL defined as in Ann Arbor staging?
Stage I — Involvement of a single lymph node region
(eg, cervical, axillary, inguinal, mediastinal)
or lymphoid structure such as the spleen, thymus, or Waldeyer’s ring.
What staging classification is used for paediatric Hodgkin lymphoma?
Ann Arbor staging with Cotswolds modifications
What is stage II in Ann Arbor staging?
Stage II —
Involvement of 2 or more lymph node regions or lymph node structures on the same side of the diaphragm.
Are nodes in the mediastinum all counted as the same LN region?
Is hilar nodes counted as the same region as mediastinum?
All nodal disease within the mediastinum is considered to be a single lymph node region.
Hilar involvement constitutes an additional site of involvement.
What is stage III in Ann arbor staging?
Stage III — Involvement of lymph node regions or lymphoid structures on both sides of the diaphragm.
What is stage IV in Ann arbor staging?
Stage IV — Diffuse or disseminated involvement of 1 or more extranodal organs or tissue beyond that designated “E,” with or without associated lymph node involvement.
What does A or B mean?
absence (A) or presence (B) of the systemic symptoms:
- significant unexplained fever,
- night sweats,
- unexplained weight loss exceeding 10% of body weight during the 6 months prior to diagnosis.
What size is considered bulky disease in adults vs in children?
Bulky disease: A single nodal mass, in contrast to multiple smaller nodes, of 10 cm or ≥⅓ of the transthoracic diameter at any level of thoracic vertebrae as determined by CT IN ADULTS.
In children bulky = > 6cm
What does E mean?
The designation “E” refers to extranodal contiguous extension (ie, proximal or contiguous extranodal disease) that can be encompassed within an irradiation field appropriate for nodal disease of the same anatomic extent. More extensive extranodal disease is designated stage IV.
What is the Deuville scoring system?
The Deauville score (also known as the 5-point scale) is a purely visual method of standardizing the interpretation of post-treatment PET scans for primary nodal lymphoma allowing for the comparison of scans performed using different machines at different centers.
The Deauville score uses a patient’s FDG uptake in the mediastinal blood pool and liver as an internal control. FDG uptake is always present in these 2 sites, with higher levels consistently seen in the liver.
The Deauville score interprets FDG avidity of suspected disease (most intense uptake in a site of initial disease) in relation to FDG uptake in these 2 locations.
What is a Deauville score 1?
1 = No uptake
what is a Deauville score 2?
2 = Uptake ≤ mediastinal blood pool
What is a Deauville score 3?
3 = Uptake > mediastinal blood pool but ≤ liver
What is a Deauville score 4?
4 = Uptake moderately more than liver uptake, at any site
What is a Deauville score 5?
5 = Uptake markedly higher than liver (ie, 2 to 3 times the maximum SUV in the liver) and/or new lesions
