Staph

Question 1

what disease is characterized by formation of localized perioral erythema

Answer 1

Staphylococcal Scaled Skin Syndrome

Question 2

what is meant by desquamation of skin around the mouth and what disease is this seen in

Answer 2

shedding of skin around the mouth and this is seen in SSSS(staphylococcal Scaled Skin syndrome)

Question 3

what are some characteristics seen in Staphylococcal Scaled Skin syndrome

Answer 3

Desquamation of skin around the mouth
Bilsters full of clear fluid
formation of localized periroral erythema

Question 4

what causes SSSS

Answer 4

S.aureus

Question 5

what are some characteristics of Bullous impetigo

Answer 5

Localized blisters containing culture (pustules)

Question 6

characteristics of impetigo

Answer 6

Young demographic
face and limbs are targeted
Macule development into a pustule
redned skin due to congestion of pilli

Question 7

what are the charateristics of folliculitis

Answer 7

around hair follicles
folicle base is raised and red puss collects beneath the surface
pus is present

Question 8

what disease is referred to as boils and what are some characteristics

Answer 8

Furuncles
progression of folliculitis
large painful nodules due to blockage of sweat gland

Question 9

what type of infection results from the combination of furuncles

Answer 9

Carbuncles
these extend deeper into the host tissue
may reslut in bactermia (infected blood)
chills and a fever

Question 10

what is the cause of prosthetic infections

Answer 10

staph epidermidis

Question 11

why are these staph infections which target the skin associated with extremities and surface of the skin?

Answer 11

because these organisms are very sensitive to heat

Question 12

what type of antibiotic should be used to treat a staph infection

Answer 12

Vancomycin

Question 13

what are the causes for staph diseases

Answer 13

toxin production and direct invasion and destruction of the host tissue

Question 14

what are some virulence factors of staph

Answer 14

capsule–> contains a polyscacharide layer which aids in evasion of phagocytosis

Endotoxin activity

Protein A- located on the capsule surface which prevents antigen binding

Teichoic acid- aids in attachment to mucosal surfaces

Clumping- coagulase causes aggregation

MSCRAMMs- Microbial surface components` recognizing adhesive matrix molecules (pretty much jus aids in attachment to host proteins)