Staph aureus virulent factors Flashcards
List the virulence factors of Staph aureus.
- Coagulase
- Hyaluronidase
- Deoxyribonuclease
- Lipase
- Staphylokinase
- Beta-lactamase
List staph aureus toxins.
Superantigens
Exfoliative toxins
Alpha, beta and delta toxins
What is function of coagulase?
Coagulation of plasma and coats bacterial cell wall for protection.
What is the function of hyaluronidase?
It breaks down hyaluronic acid to enable spread.
What is the function of deoxyribonuclease?
It breaks down the DNA.
What is the function of lipase?
It breaks down lipids.
What is the function of staphylokinase?
It dissolves fibrin and aids in spread.
What is the function of beta-lactamase?
It helps the organism to become antibiotic resistant.
What is the function of Protein A?
It is located on the surface of staph aureus and binds to the Fc region of the antibodies.
It impairs phagocytosis and cripples antibody mediated response.
