Statins Flashcards

1
Q

What class of medications do statins belong to?

A

Statins belong to the class of medications known as HMG-CoA reductase inhibitors.

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2
Q

What is the primary action of statins?

A

The primary action of statins is to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase.

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3
Q

Which condition are statins primarily indicated for?

A

Statins are primarily indicated for the treatment of hyperlipidemia and the prevention of cardiovascular disease.

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4
Q

True or False: Statins can help reduce the risk of heart attack and stroke.

A

True.

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5
Q

What is a common starting dosage for atorvastatin?

A

A common starting dosage for atorvastatin is 10 to 20 mg once daily.

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6
Q

Fill in the blank: Statins are often prescribed in conjunction with _____ for better cardiovascular outcomes.

A

lifestyle changes.

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7
Q

What are some common adverse effects of statins?

A

Common adverse effects of statins include muscle pain, liver enzyme abnormalities, and digestive issues.

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8
Q

Which laboratory test is important to monitor in patients taking statins?

A

Liver function tests are important to monitor in patients taking statins.

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9
Q

True or False: Statins can interact with certain medications, such as some antibiotics and antifungals.

A

True.

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10
Q

What should a nurse consider when educating a patient about statin therapy?

A

A nurse should consider discussing potential side effects, the importance of adherence, and the need for regular follow-up appointments.

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11
Q

What is the mechanism of action for statins?

A

Statins work by blocking the production of cholesterol in the liver.

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12
Q

Name one contraindication for statin use.

A

Active liver disease is a contraindication for statin use.

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13
Q

What is the recommended route of administration for statins?

A

The recommended route of administration for statins is oral.

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14
Q

What is the maximum daily dose for simvastatin?

A

The maximum daily dose for simvastatin is 40 mg.

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15
Q

True or False: Statins can cause rhabdomyolysis in rare cases.

A

True.

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16
Q

What should patients avoid while taking statins?

A

Patients should avoid consuming large quantities of grapefruit juice while taking statins.

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17
Q

Fill in the blank: Statins can lower _____ levels in the blood.

A

LDL cholesterol.

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18
Q

What is the role of coenzyme Q10 in relation to statins?

A

Coenzyme Q10 may help alleviate muscle-related side effects associated with statin use.

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19
Q

What are some common statin medications?

A

Common statin medications include atorvastatin, simvastatin, and rosuvastatin.

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20
Q

True or False: Statins are safe for use during pregnancy.

A

False.

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21
Q

What lifestyle modifications should be encouraged alongside statin therapy?

A

Dietary changes, increased physical activity, and smoking cessation should be encouraged.

22
Q

What is the effect of statins on HDL cholesterol?

A

Statins may have a modest effect in increasing HDL cholesterol levels.

23
Q

What is the significance of the ‘statin benefit groups’?

A

Statin benefit groups are guidelines that help identify patients who would benefit most from statin therapy.

24
Q

Name one potential drug interaction with statins.

A

Statins can interact with warfarin, increasing the risk of bleeding.

25
What is a nursing consideration when administering statins?
Monitor for signs of muscle pain or weakness in patients taking statins.
26
What is the drug class of Crestor?
Statin
27
What is the primary action of Crestor?
Inhibits HMG-CoA reductase to lower cholesterol levels
28
What is the usual starting dosage of Crestor for adults?
10 mg once daily
29
True or False: Crestor can be taken with or without food.
True
30
What are the primary indications for prescribing Crestor?
Hyperlipidemia and prevention of cardiovascular disease
31
What is a common adverse effect of Crestor?
Muscle pain or weakness
32
Fill in the blank: Crestor should be used with caution in patients with __________ impairment.
liver
33
What serious adverse effect should be monitored when using Crestor?
Rhabdomyolysis
34
Which of the following medications can interact with Crestor? (A) Antacids (B) Warfarin (C) Niacin
C) Niacin
35
What is the maximum recommended dosage of Crestor for adults?
40 mg once daily
36
True or False: Grapefruit juice can increase the effects of Crestor.
False
37
What should a nurse assess before administering Crestor?
Liver function tests
38
What lifestyle modifications should be encouraged alongside Crestor therapy?
Dietary changes, exercise, and smoking cessation
39
Fill in the blank: Patients taking Crestor should be monitored for signs of __________.
muscle damage
40
What is the action of Crestor on LDL cholesterol?
Reduces LDL cholesterol levels
41
What is the recommended dosage adjustment for patients with renal impairment?
Start at a lower dose and titrate cautiously
42
True or False: Crestor is safe to use during pregnancy.
False
43
What monitoring is recommended for patients on Crestor?
Lipid levels and liver enzymes
44
What is the mechanism by which Crestor lowers triglycerides?
By reducing hepatic production of triglycerides
45
Fill in the blank: The generic name for Crestor is __________.
rosuvastatin
46
What should patients be advised regarding alcohol consumption while on Crestor?
Limit or avoid alcohol
47
True or False: Crestor can be prescribed to children aged 10 and older.
True
48
What is the initial dosage of Crestor for pediatric patients?
5 mg once daily
49
What is a common side effect that might lead to discontinuation of Crestor?
Gastrointestinal discomfort
50
What should be done if a patient experiences severe muscle pain while on Crestor?
Discontinue the medication and evaluate for rhabdomyolysis
51
What is the action of Crestor on HDL cholesterol?
Increases HDL cholesterol levels
52
Fill in the blank: Crestor is contraindicated in patients with active __________ disease.
liver